There are 10 ways to get from Brussels to Setúbal by plane, bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Brussels Airport, bus
best- Fly from Brussels Airport (BRU) to Lisbon-Portela Airport (LIS)plane BRU - LIS
- Take the bus from Gare do Oriente 21-C to Avenida Dom João IIbus
6h 8m€81–297Train, bus
- Take the train from Brussel-Zuid / Bruxelles-Midi to Paris Nordtrain
- Take the train from Paris Gare De Lyon to Barcelona-Santstrain Tgv
- Take the train from Barcelona-Sants to Zaragoza-Deliciastrain Ave
- Take the bus from Estación Central de Autobuses de Zaragoza to Setúbalbus
22h 32m€339–662Train, bus via Córdoba
- Take the train from Brussel-Zuid / Bruxelles-Midi to Paris Nordtrain
- Take the train from Paris Gare De Lyon to Barcelona-Santstrain Tgv
- Take the train from Barcelona-Sants to Cordoba-Centraltrain
- Take the bus from Córdoba, Estación de Autobuses to Badajozbus
- Take the bus from Badajoz to Setúbalbus
24h 15m€393–794Drive 2,023.2 km
- Drive from Brussels to Setúbalcar 2,023.2 km
20h 10m€322–464Train to Brussels South Charleroi Airport, fly, bus
- Take the train from Bruxelles-Central to Charleroi-Centraltrain
- Fly from Brussels South Charleroi Airport (CRL) to Lisbon-Portela Airport (LIS)plane CRL - LIS
- Take the bus from Gare do Oriente 21-C to Avenida Dom João IIbus
7h 18m€93–394Train to Amsterdam Airport Schiphol, fly, bus
- Take the train from Brussel-Zuid / Bruxelles-Midi to Schiphol Airporttrain
- Fly from Amsterdam Airport Schiphol (AMS) to Lisbon-Portela Airport (LIS)plane AMS - LIS
- Take the bus from Gare do Oriente 21-C to Avenida Dom João IIbus
7h 39m€159–449Train, train to Eindhoven Airport, fly, bus
- Take the train from Bruxelles-Central to Bredatrain
- Take the train from Breda to Eindhoven Centraaltrain
- Fly from Eindhoven Airport (EIN) to Lisbon-Portela Airport (LIS)plane EIN - LIS
- Take the bus from Gare do Oriente 21-C to Avenida Dom João IIbus
8h 54m€108–423Train to Rotterdam The Hague Airport, fly, bus
- Take the train from Brussel-Zuid / Bruxelles-Midi to Rotterdam Centraaltrain
- Fly from Rotterdam The Hague Airport (RTM) to Lisbon-Portela Airport (LIS)plane RTM - LIS
- Take the bus from Gare do Oriente 21-C to Avenida Dom João IIbus
7h 36m€293–794Train, bus #2
- Take the train from Brussel-Zuid to Paris Nordtrain
- Take the bus from Paris - Porte Dauphine to Estação Rodoviária de Lisboa Orientebus
- Take the bus from Gare do Oriente 21-C to Avenida Dom João IIbus
27h 29m€161–300Bus
- Take the bus from Brussels-North train station to Lisbonbus FlixBus N1143
- Take the bus from Gare do Oriente 21-C to Avenida Dom João IIbus 4720 / ...
30h 21m€185–276
Brussels to Setúbal by train and bus
Comparing Your Travel Options
The cheapest way to get from Brussels to Setúbal is to fly and bus which costs €80 - €300 and takes 6h 8m.
The fastest way to get from Brussels to Setúbal is to fly and bus which takes 6h 8m and costs €80 - €300.
No, there is no direct bus from Brussels station to Setúbal. However, there are services departing from Brussels-North train station and arriving at Avenida Dom João II via Gare do Oriente 21-C. The journey, including transfers, takes approximately 30h 21m.
The distance between Brussels and Setúbal is 1778 km. The road distance is 2023.2 km.
The best way to get from Brussels to Setúbal without a car is to train and bus which takes 22h 32m and costs €330 - €700.
It takes approximately 6h 8m to get from Brussels to Setúbal, including transfers.
Brussels to Setúbal bus services, operated by FlixBus, depart from Brussels-North train station.
Brussels to Setúbal bus services, operated by FlixBus, arrive at Lisbon station.
Setúbal is 1h behind Brussels. It is currently 1:28 AM in Brussels and 12:28 AM in Setúbal.
Yes, the driving distance between Brussels to Setúbal is 2023 km. It takes approximately 20h 10m to drive from Brussels to Setúbal.
What companies run services between Brussels, Belgium and Setúbal, Portugal?
You can take a bus from Brussels-North train station to Avenida Dom João II via Lisbon and Gare do Oriente 21-C in around 30h 21m.
- Website
- ryanair.com
Flights from Brussels South Charleroi Airport to Lisbon-Portela Airport
- Ave. Duration
- 2h 50m
- When
- Every day
- Estimated price
- €70–310
Flights from Brussels South Charleroi Airport to Lisbon-Portela Airport via Toulouse
- Ave. Duration
- 4h 55m
- When
- Wednesday, Thursday, and Sunday
- Estimated price
- €70–310
Flights from Brussels South Charleroi Airport to Lisbon-Portela Airport via Sevilla
- Ave. Duration
- 6h 5m
- When
- Tuesday and Saturday
- Estimated price
- €70–310
Flights from Eindhoven Airport to Lisbon-Portela Airport
- Ave. Duration
- 3h
- When
- Monday, Thursday, and Saturday
- Estimated price
- €80–310
Flights from Eindhoven Airport to Lisbon-Portela Airport via Sevilla
- Ave. Duration
- 5h 32m
- When
- Thursday
- Estimated price
- €80–310
Flights from Eindhoven Airport to Lisbon-Portela Airport via London Stansted
- Ave. Duration
- 5h 50m
- When
- Friday, Wednesday, and Tuesday
- Estimated price
- €80–310
- Phone
- +44 (0)3432 186 186
- Website
- Eurostar
Train from Brussel-Zuid / Bruxelles-Midi to Paris Nord
- Ave. Duration
- 1h 23m
- Frequency
- Every 20 minutes
- Estimated price
- €100–170
- Website
- Eurostar
Train from Brussel-Zuid / Bruxelles-Midi to Paris Nord
- Ave. Duration
- 1h 23m
- Frequency
- Every 20 minutes
- Estimated price
- €100–170
- Website
- Eurostar
Train from Brussel-Zuid / Bruxelles-Midi to Schiphol Airport
- Ave. Duration
- 1h 37m
- Frequency
- Hourly
- Estimated price
- €60–110
- Website
- Eurostar
Train from Brussel-Zuid / Bruxelles-Midi to Rotterdam Centraal
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €45–80
- Website
- Eurostar
Train from Brussel-Zuid to Paris Nord
- Ave. Duration
- 1h 33m
- Frequency
- 5 times a day
- Estimated price
- €100–170
- Website
- Eurostar
- Phone
- +351 210 418 800
- [email protected]
- Website
- carrismetropolitana.pt
Bus from Gare do Oriente 21-C to Avenida Dom João II
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €3–6
- Schedules at
- carrismetropolitana.pt
- On-board Ticket
- €3–6
Bus from Gare do Oriente 21-C to Avenida Dom João II
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €3–6
- Schedules at
- carrismetropolitana.pt
- On-board Ticket
- €3–6
Bus from Gare do Oriente 21-C to Avenida Dom João II
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €3–6
- Schedules at
- carrismetropolitana.pt
- On-board Ticket
- €3–6
Bus from Gare do Oriente 21-C to Avenida Dom João II
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €3–6
- Schedules at
- carrismetropolitana.pt
- On-board Ticket
- €3–6
Bus from Gare do Oriente 21-C to Avenida Dom João II
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €3–6
- Schedules at
- carrismetropolitana.pt
- On-board Ticket
- €3–6
Bus from Gare do Oriente 21-C to Avenida Dom João II
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €3–6
- Schedules at
- carrismetropolitana.pt
- On-board Ticket
- €3–6
Bus from Gare do Oriente 21-C to Avenida Dom João II
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €3–6
- Schedules at
- carrismetropolitana.pt
- On-board Ticket
- €3–6
Want to know more about travelling around Portugal
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Booking & Getting There
Book your Brussels to Setúbal bus tickets online with Omio.
There are 1447+ hotels available in Setúbal.









