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How to get fromBrussels to Sienaby plane, train, train (Eurostar, Trenitalia), bus, or car

Find Transport to Siena

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There are 9 ways to get from Brussels to Siena by plane, train, train (Eurostar, Trenitalia), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Brussels Airport to Florence Peretola Airport, train

    best
    1. Fly from Brussels Airport (BRU) to Florence Peretola Airport (FLR)plane plane BRU - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    6h 44m
    €80–241

  2. Train to Brussels South Charleroi Airport, fly to Pisa International Airport, train

    cheapest
    1. Take the train from Bruxelles-Central to Charleroi-Centraltrain train
    2. Fly from Brussels South Charleroi Airport (CRL) to Pisa International Airport (PSA)plane plane CRL - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    7h 41m
    €72–256

  3. Train

    1. Take the train from Brussel-Zuid / Bruxelles-Midi to Chambery Challes Les Eauxtrain train
    2. Take the train from Chambery Challes Les Eaux to Milano Centraletrain train Fr
    3. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    13h 47m
    €389–642

  4. Bus

    1. Take the bus from Bruxelles - Rue du Progrès to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 1518 / ...
    18h 56m
    €164–225

  5. Drive  1,231.4 km

    1. Drive from Brussels to Sienacar car 1,231.4 km
    12h 39m
    €200–288

  6. Fly Brussels Airport to Bologna Guglielmo Marconi Airport, train

    1. Fly from Brussels Airport (BRU) to Bologna Guglielmo Marconi Airport (BLQ)plane plane BRU - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    7h 12m
    €87–281

  7. Train to Amsterdam Airport Schiphol, fly to Florence Peretola Airport, train

    1. Take the train from Brussel-Zuid to Schiphol Airport Train Stationtrain train
    2. Fly from Amsterdam Airport Schiphol (AMS) to Florence Peretola Airport (FLR)plane plane AMS - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 36m
    €134–297

  8. Train to Brussels South Charleroi Airport, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the train from Bruxelles-Central to Charleroi-Centraltrain train
    2. Fly from Brussels South Charleroi Airport (CRL) to Bologna Guglielmo Marconi Airport (BLQ)plane plane CRL - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    8h 31m
    €80–278

  9. Bus via Genoa

    1. Take the bus from Brussels-North train station to Genoabus bus FlixBus N506
    2. Take the bus from Genoa to Sienabus bus 516 / ...
    21h 40m
    €127–189

Brussels to Siena by train

Calendar2Weekly Trains
Duration13h 47mAverage Duration
Ticket€389Cheapest Price
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Comparing Your Travel Options

Map of how to get from Brussels to Siena.ExpandLaunch map view
  • Distance: 1,046.9 km
  • Duration: 6h 44m

What companies run services between Brussels, Belgium and Siena, Italy?

You can take a train from Brussel-Zuid / Bruxelles-Midi to Siena via Chambery Challes Les Eaux, Milano Centrale, and Firenze S.M.N. in around 13h 47m. Alternatively, you can take a bus from Bruxelles - Rue du Progrès to Siena via Florence Villa Constanza Bus Station in around 18h 56m.

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