There are 6 ways to get from Bryan to Buffalo by bus (Amtrak), train (Amtrak), car, plane, bus (Amtrak, Greyhound), train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Bryan Amtrak Station to Toledobus
- Take the bus from Toledo to Clevelandbus
- Take the bus from Cleveland, OH to Buffalo, NYbus
8h 20m$49–133Train (Amtrak)
- Take the train from Bryan Amtrak Station to Buffalo Depew Stationtrain Lake Shore Limited
8h 29m$115–369Drive 352.8 mi
- Drive from Bryan to Buffalocar 352.8 mi
6h 11m$65–93Drive to Fort Wayne International Airport, fly
- Drive from Bryan to Fort Wayne International Airport (FWA)car
- Fly from Fort Wayne International Airport (FWA) to Buffalo Niagara International Airport (BUF)plane FWA - BUF
5h 24m$87–524Bus via Brook Park
- Take the bus from Bryan Amtrak Station to Toledobus
- Take the bus from Toledo Bus Stop to Cleveland Bus Stationbus
- Take the bus from Cleveland Bus Station to Buffalobus
8h 40m$65–118Train, bus to Detroit, fly
- Take the train from Bryan Amtrak Station to Toledotrain
- Take the bus from Toledo to Dearbornbus
- Fly from Detroit (DTW) to Buffalo Niagara International Airport (BUF)plane DTW - BUF
7h 42m$125–651
Bryan to Buffalo by bus
Questions & Answers
The cheapest way to get from Bryan to Buffalo is to bus via Brook Park which costs $65 - $120 and takes 8h 40m.
The fastest way to get from Bryan to Buffalo is to drive and fly which takes 5h 24m and costs $85 - $550.
No, there is no direct bus from Bryan station to Buffalo. However, there are services departing from Bryan Amtrak Station and arriving at Buffalo, NY via Toledo and Cleveland, OH. The journey, including transfers, takes approximately 8h 20m.
No, there is no direct train from Bryan station to Buffalo. However, there are services departing from Bryan Amtrak Station and arriving at Buffalo via Buffalo Depew Station. The journey, including transfers, takes approximately 8h 29m.
The distance between Bryan and Buffalo is 366 miles. The road distance is 354.9 miles.
The best way to get from Bryan to Buffalo without a car is to bus which takes 8h 20m and costs $45 - $140.
It takes approximately 8h 20m to get from Bryan to Buffalo, including transfers.
Bryan to Buffalo bus services, operated by Amtrak, depart from Bryan Amtrak Station.
Bryan to Buffalo train services, operated by Amtrak, depart from Bryan Amtrak Station.
The best way to get from Bryan to Buffalo is to bus which takes 8h 20m and costs $45 - $140. Alternatively, you can train, which costs $110 - $370 and takes 8h 29m.
What companies run services between Bryan, OH, USA and Buffalo, NY, USA?
You can take a bus from Bryan Amtrak Station to Buffalo, NY via Toledo and Cleveland, OH in around 8h 20m. Alternatively, Amtrak operates a train from Bryan Amtrak Station to Buffalo Depew Station twice daily. Tickets cost $110–230 and the journey takes 7h 8m.
- Website
- delta.com
Flights from Fort Wayne International Airport to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $75–480
Flights from Fort Wayne International Airport to Buffalo Niagara International Airport via Atlanta
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $160–750
Flights from Detroit to Buffalo Niagara International Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- $80–550
- Website
- aa.com
Flights from Fort Wayne International Airport to Buffalo Niagara International Airport via Chicago O'Hare
- Ave. Duration
- 5h 18m
- When
- Every day
- Estimated price
- $100–600
Flights from Fort Wayne International Airport to Buffalo Niagara International Airport via Charlotte
- Ave. Duration
- 6h 3m
- When
- Every day
- Estimated price
- $140–700
- Website
- united.com
Flights from Fort Wayne International Airport to Buffalo Niagara International Airport via Chicago O'Hare
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $100–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Bryan Amtrak Station to Buffalo Depew Station
- Ave. Duration
- 7h 8m
- Frequency
- Twice daily
- Estimated price
- $110–230
- Website
- https://www.amtrak.com/home.html
Train from Bryan Amtrak Station to Toledo
- Ave. Duration
- 1h 26m
- Frequency
- Twice daily
- Estimated price
- $17–40
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Bryan Amtrak Station to Toledo
- Ave. Duration
- 1h 25m
- Frequency
- Once a week
- Estimated price
- $20–29
- Website
- https://www.amtrak.com/home.html
Bus from Bryan Amtrak Station to Toledo
- Ave. Duration
- 1h 25m
- Frequency
- Once a week
- Estimated price
- $20–29
- Website
- https://www.amtrak.com/home.html
Bus from Toledo to Dearborn
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $24–35
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888-378-3823
- [email protected]
- Website
- baronsbus.com
Bus from Toledo to Cleveland
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $11–45
- Website
- https://baronsbus.com
Bus from Cleveland, OH to Buffalo, NY
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $18–60
- Website
- https://baronsbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Toledo Bus Stop to Cleveland Bus Station
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a day
- Estimated price
- $15–30
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Buffalo
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $30–60
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
Bryan to Buffalo bus services, operated by Amtrak, arrive at Toledo station.
Bryan to Buffalo train services, operated by Amtrak, arrive at Buffalo Depew Station.
Yes, the driving distance between Bryan to Buffalo is 355 miles. It takes approximately 6h 11m to drive from Bryan to Buffalo.
Book your Bryan to Buffalo train tickets online with Omio.
There are 254+ hotels available in Buffalo.











