There are 5 ways to get from Bryson City to Santee by car, plane, bus, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive, fly to Columbia
best- Drive from Bryson City to Atlanta-Airport-ATLcar
- Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Columbia (CAE)plane ATL - CAE
- Drive from Columbia-Airport-CAE to Santeecar
5h 18m$160–910Drive 268.1 mi
cheapest- Drive from Bryson City to Santeecar 268.1 mi
4h 40m$49–71Drive, bus
- Drive from Bryson City to Asheville, NCcar
- Take the bus from Asheville, NC to Winston Salem(Trans Center)bus
- Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Orangeburgbus
11h 35m$150–234Drive, fly to Charleston International Airport
- Drive from Bryson City to Atlanta-Airport-ATLcar
- Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Charleston International Airport (CHS)plane ATL - CHS
- Drive from Charleston-Airport-CHS to Santeecar
5h 32m$430–1,060Drive, shuttle, bus
- Drive from Bryson City to Hot Springscar
- Take a shuttle bus from Hot Springs to Black Bear Resort
- Take a shuttle bus from Black Bear Resort to Boone
- Take the bus from ASU Peacock Hall Boone to Charlotte Airportbus
- Take the bus from Charlotte Bus Station to Orangeburgbus
14h 44m$434–507
Hartsfield-Jackson Atlanta International Airport (ATL) to Columbia (CAE) flights
Questions & Answers
The cheapest way to get from Bryson City to Santee is to drive which costs $45 - $75 and takes 4h 40m.
The fastest way to get from Bryson City to Santee is to drive which takes 4h 40m and costs $45 - $75.
The distance between Bryson City and Santee is 419 miles. The road distance is 269.7 miles.
It takes approximately 5h 18m to get from Bryson City to Santee, including transfers.
Yes, the driving distance between Bryson City to Santee is 270 miles. It takes approximately 4h 40m to drive from Bryson City to Santee.
There are 41+ hotels available in Santee.
What companies run services between Bryson City, NC, USA and Santee, SC, USA?
There is no direct connection from Bryson City to Santee. However, you can drive to Atlanta-Airport-ATL airport, fly to Columbia (CAE), then drive to Santee. Alternatively, you can take a vehicle from Bryson City to Santee via Asheville, NC, Winston Salem(Trans Center), Charlotte Bus Station, and Orangeburg in around 11h 35m.
- Website
- delta.com
Flights from Hartsfield-Jackson Atlanta International Airport to Columbia
- Ave. Duration
- 1h 3m
- When
- Every day
- Estimated price
- $120–850
Flights from Hartsfield-Jackson Atlanta International Airport to Charleston International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $55–370
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Asheville, NC to Winston Salem(Trans Center)
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $22–45
- Website
- https://www.greyhound.com/
Bus from Winston Salem(Trans Center) to Charlotte Bus Station
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $11–22
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Orangeburg
- Ave. Duration
- 4h
- Frequency
- Twice daily
- Estimated price
- $25–50
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Orangeburg
- Ave. Duration
- 4h
- Frequency
- Twice daily
- Estimated price
- $25–50
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Charlotte Bus Station to Orangeburg
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $26–45
- Schedules at
- flixbus.com
Bus from Charlotte Bus Station to Orangeburg
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $26–45
- Schedules at
- flixbus.com
- Phone
- +1-423-725-5988
- Website
- blackbearresorttn.com
Shuttle from Hot Springs to Black Bear Resort
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- https://blackbearresorttn.com/Shuttle-Service.html
Shuttle from Black Bear Resort to Boone
- Ave. Duration
- 1h
- Frequency
- On demand
- Estimated price
- $86
- Website
- https://blackbearresorttn.com/Shuttle-Service.html
- Phone
- +1 828-327-2340
- [email protected]
- Website
- hickoryhop.com
Bus from ASU Peacock Hall Boone to Charlotte Airport
- Ave. Duration
- 2h 30m
- Frequency
- Every 4 hours
- Estimated price
- $90–110
- Schedules at
- hickoryhop.com
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