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How to get fromBuffalo Airport (BUF) to San Diegoby plane, train (Amtrak), bus (Greyhound, Amtrak), car, train, or bus

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There are 8 ways to get from Buffalo Airport (BUF) to San Diego by plane, train (Amtrak), bus (Greyhound, Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to San Diego International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to San Diego International Airport (SAN)plane plane BUF - SAN
    6h 45m
    $220–950

  2. Fly to Los Angeles International Airport, train

    cheapest
    1. Fly from Buffalo Niagara International Airport (BUF) to Los Angeles International Airport (LAX)plane plane BUF - LAX
    2. Take the train from Los Angeles to San Diegotrain train
    10h 9m
    $205–754

  3. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    3. Take the train from Fullerton Amtrak Station to San Diegotrain train
    2d 11h
    $870–1,973

  4. Bus

    1. Take the bus from Buffalo, NY to Columbus - Mound Stbus bus
    2. Take the bus from Columbus to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus
    4. Take the bus from Los Angeles to San Diegobus bus
    2d 16h
    $417–838

  5. Drive 2,539.4 mi

    1. Drive from Buffalo Airport (BUF) to San Diegocar car 2,539.4 mi
    41h 47m
    $464–670

  6. Fly to Mcclellan–Palomar Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Mcclellan–Palomar Airport (CLD)plane plane BUF - CLD
    2. Take the train from Carlsbad Village Station to San Diego - Santa Fe Depottrain train
    11h 24m
    $221–886

  7. Fly to John Wayne Airport Orange County, train

    1. Fly from Buffalo Niagara International Airport (BUF) to John Wayne Airport Orange County (SNA)plane plane BUF - SNA
    2. Take the train from Fullerton Amtrak Station to San Diegotrain train
    12h 39m
    $295–1,125

  8. Bus, train

    1. Take the bus from Buffalo Niagara International Airport to Toronto Pearson Airportbus bus
    2. Take the bus from Toronto Pearson Airport to Detroit Bus Stationbus bus
    3. Take the bus from Detroit to Chicago Union Stationbus bus
    4. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    5. Take the train from Fullerton Amtrak Station to San Diegotrain train
    2d 17h
    $822–1,798

Buffalo Airport (BUF) to San Diego by bus, taxi, and train (Amtrak)

Calendar7Weekly Services
Duration2d 11hAverage Duration
Ticket$870Cheapest Price
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Questions & Answers

Map of how to get from Buffalo Airport (BUF) to San Diego.ExpandLaunch map view
  • Distance: 2,192.4 mi
  • Duration: 6h 45m

What companies run services between Buffalo Airport (BUF), USA and San Diego, CA, USA?

Southwest Airlines, Delta, and United Airlines fly from Buffalo Niagara International Airport (BUF) to San Diego International Airport (SAN) every 3 hours. Alternatively, you can take a bus from BNIA Driveway & BNIA Terminal to San Diego via Washington Street & Eagle Street, Buffalo Depew Station, Chicago Union Station, and Fullerton Amtrak Station in around 2d 11h.

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