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How to get fromBuffalo Central Terminal to Bostonby bus (Greyhound), train (Amtrak), car, plane, train, bus (Flixbus), or ferry

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There are 6 ways to get from Buffalo Central Terminal to Boston by bus (Greyhound), train (Amtrak), car, plane, train, bus (Flixbus), or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Buffalo to Bostonbus bus Greyhound US0171
    11h 45m
    $82–132

  2. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Bostontrain train Lake Shore Limited
    13h 11m
    $262–422

  3. Drive  451.2 mi

    1. Drive from Buffalo Central Terminal to Bostoncar car 451.2 mi
    7h 59m
    $83–119

  4. Fly to Laguardia Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Laguardia Airport (LGA)plane plane BUF - LGA
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train
    9h 32m
    $200–716

  5. Bus via Ithaca (Flixbus)

    1. Take the bus from Buffalo to Ithacabus bus FlixBus 2685 / ...
    2. Take the bus from Ithaca to Bostonbus bus FlixBus 2691
    14h 11m
    $88–132

  6. Fly to Provincetown Municipal Airport, ferry

    1. Fly from Buffalo Niagara International Airport (BUF) to Provincetown Municipal Airport (PVC)plane plane BUF - PVC
    2. Take the ferry from MacMillan Pier, Provincetown, MA to World Trade Center Pier, Boston, MAferry ferry
    9h 16m
    $163–580

Buffalo Central Terminal to Boston by foot and bus (Flixbus)

Calendar3Weekly Services
Duration14h 11mAverage Duration
Ticket$88Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo Central Terminal to Boston.ExpandLaunch map view
  • Distance: 476.2 mi
  • Duration: 11h 45m

What companies run services between Buffalo Central Terminal, NY, USA and Boston, MA, USA?

Greyhound USA operates a bus from Buffalo to Boston once daily. Tickets cost $80–130 and the journey takes 10h 5m. Alternatively, Amtrak operates a train from Buffalo Depew Station to Boston once daily. Tickets cost $260–420 and the journey takes 11h 27m.

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