There are 9 ways to get from Buffalo Depew Station to Gatlinburg by plane, taxi, train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Buffalo Niagara International Airport to Mcghee Tyson Airport, taxi
best- Fly from Buffalo Niagara International Airport (BUF) to Mcghee Tyson Airport (TYS)plane BUF - TYS
- Take the taxi from Mcghee Tyson Airport (TYS) to Gatlinburgtaxi
5h 4m$354–1,177Fly Buffalo Niagara International Airport to Asheville Regional Airport, drive
cheapest- Fly from Buffalo Niagara International Airport (BUF) to Asheville Regional Airport (AVL)plane BUF - AVL
- Drive from Asheville-Airport-AVL to Gatlinburgcar
6h 12m$124–540Train, bus, taxi
- Take the train from Buffalo to New York Penn Stationtrain
- Take the bus from New York, NY to Knoxville, TNbus Ny
- Take the taxi from Knoxville, TN to Gatlinburgtaxi
23h 19m$406–626Train, bus, drive
- Take the train from Buffalo Depew Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Greensborotrain
- Take the bus from Greensboro Bus Stop to Asheville, NCbus
- Drive from Asheville, NC to Gatlinburgcar
25h 38m$337–694Drive 704.6 mi
- Drive from Buffalo Depew Station to Gatlinburgcar 704.6 mi
12h 5m$129–186Fly Buffalo Niagara International Airport to Nashville, drive
- Fly from Buffalo Niagara International Airport (BUF) to Nashville (BNA)plane BUF - BNA
- Drive from Nashville-Airport-BNA to Gatlinburgcar
5h 49m$149–622Train to Rochester, fly to Mcghee Tyson Airport, taxi
- Take the train from Buffalo Depew Station to Rochestertrain
- Fly from Rochester (ROC) to Mcghee Tyson Airport (TYS)plane ROC - TYS
- Take the taxi from Mcghee Tyson Airport (TYS) to Gatlinburgtaxi
6h 59m$376–1,338Bus, drive
- Take the bus from Buffalo to Port Authority Bus Terminalbus
- Take the bus from New York to Knoxvillebus Nyc
- Drive from Knoxville to Gatlinburgcar
24h 42m$166–412Bus, taxi
- Take the bus from Buffalo to New York Midtownbus
- Take the bus from New York, NY to Knoxville, TNbus Ny
- Take the taxi from Knoxville, TN to Gatlinburgtaxi
26h 3m$360–475
Buffalo Niagara International Airport (BUF) to Mcghee Tyson Airport (TYS) flights
Questions & Answers
The cheapest way to get from Buffalo Depew Station to Gatlinburg is to drive which costs $120 - $190 and takes 12h 5m.
The fastest way to get from Buffalo Depew Station to Gatlinburg is to fly and taxi which takes 5h 4m and costs $350 - $1,200.
The distance between Buffalo Depew Station and Gatlinburg is 613 miles. The road distance is 708.7 miles.
The best way to get from Buffalo Depew Station to Gatlinburg without a car is to train and bus and taxi which takes 23h 19m and costs $400 - $650.
It takes approximately 5h 4m to get from Buffalo Depew Station to Gatlinburg, including transfers.
Yes, the driving distance between Buffalo Depew Station to Gatlinburg is 709 miles. It takes approximately 12h 5m to drive from Buffalo Depew Station to Gatlinburg.
There are 5795+ hotels available in Gatlinburg.
What companies run services between Buffalo Depew Station, NY, USA and Gatlinburg, TN, USA?
There is no direct connection from Buffalo Depew Station to Gatlinburg. However, you can take the taxi to Buffalo-Airport-BUF airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Gatlinburg. Alternatively, you can take the train to New York Penn Station, walk to 34 St-Herald Sq, take the subway to East Broadway, walk to New York, NY, take the bus to Knoxville, TN, then take the taxi to Gatlinburg.
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Mcghee Tyson Airport via Detroit
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $170–950
Flights from Buffalo Niagara International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 5h 8m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $200–1,000
Flights from Buffalo Niagara International Airport to Asheville Regional Airport via Atlanta
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $110–600
Flights from Buffalo Niagara International Airport to Asheville Regional Airport via New York La Guardia
- Ave. Duration
- 5h 14m
- When
- Every day
- Estimated price
- $110–600
Flights from Buffalo Niagara International Airport to Nashville via Detroit
- Ave. Duration
- 3h 49m
- When
- Every day
- Estimated price
- $110–600
Flights from Buffalo Niagara International Airport to Nashville via Atlanta
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $130–650
Flights from Rochester to Mcghee Tyson Airport via Detroit
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $180–950
Flights from Rochester to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 49m
- When
- Every day
- Estimated price
- $210–1,000
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $180–950
Flights from Buffalo Niagara International Airport to Mcghee Tyson Airport via Reagan Washington
- Ave. Duration
- 5h 19m
- When
- Every day
- Estimated price
- $180–950
Flights from Buffalo Niagara International Airport to Asheville Regional Airport via Charlotte
- Ave. Duration
- 5h 34m
- When
- Every day
- Estimated price
- $95–500
Flights from Buffalo Niagara International Airport to Asheville Regional Airport via Philadelphia
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $100–550
Flights from Buffalo Niagara International Airport to Asheville Regional Airport via Reagan Washington
- Ave. Duration
- 5h 58m
- When
- Saturday and Sunday
- Estimated price
- $100–550
Flights from Buffalo Niagara International Airport to Asheville Regional Airport via New York La Guardia
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $110–600
Flights from Rochester to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $180–950
Flights from Rochester to Mcghee Tyson Airport via Reagan Washington
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $180–950
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Mcghee Tyson Airport via Baltimore
- Ave. Duration
- 4h 10m
- When
- Monday to Saturday
- Estimated price
- $180–950
Flights from Buffalo Niagara International Airport to Mcghee Tyson Airport via Nashville
- Ave. Duration
- 4h 35m
- When
- Sunday
- Estimated price
- $190–1,000
Flights from Buffalo Niagara International Airport to Nashville
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- $100–550
Flights from Buffalo Niagara International Airport to Nashville via Chicago Midway
- Ave. Duration
- 4h
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $120–650
Flights from Buffalo Niagara International Airport to Nashville via Baltimore
- Ave. Duration
- 4h
- When
- Sunday
- Estimated price
- $130–650
Flights from Rochester to Mcghee Tyson Airport via Baltimore
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $180–950
- Website
- united.com
Flights from Buffalo Niagara International Airport to Mcghee Tyson Airport via Washington Dulles
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $180–950
Flights from Buffalo Niagara International Airport to Asheville Regional Airport via Newark
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $110–600
Flights from Buffalo Niagara International Airport to Nashville via Washington Dulles
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $120–650
Flights from Rochester to Mcghee Tyson Airport via Washington Dulles
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $170–950
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Buffalo to New York Penn Station
- Ave. Duration
- 8h 46m
- Frequency
- Once daily
- Estimated price
- $110–290
- Website
- VIA Rail
- Escape
- $110–260
- Business
- $150–280
- Business Plus
- $160–290
- Economy
- $130–270
- Economy Plus
- $140–280
Train from Buffalo Depew Station to Rochester
- Ave. Duration
- 51 min
- Frequency
- Once daily
- Estimated price
- $16–160
- Website
- VIA Rail
- Escape
- $16–65
- Business
- $45–150
- Business Plus
- $60–160
- Economy
- $18–70
- Economy Plus
- $20–80
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Buffalo Depew Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 8h
- Frequency
- 4 times a day
- Estimated price
- $130–290
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Greensboro
- Ave. Duration
- 10h 25m
- Frequency
- Twice daily
- Estimated price
- $160–340
- Website
- Amtrak
Train from Buffalo Depew Station to Rochester
- Ave. Duration
- 51 min
- Frequency
- 5 times a day
- Estimated price
- $19–40
- Website
- Amtrak
- Phone
- +1 615-939-8887
- [email protected]
- Website
- New York to Tennessee Bus
Bus from New York, NY to Knoxville, TN
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $95–110
- Website
- New York to Tennessee Bus
- Adult One-way
- $95–110
Bus from New York, NY to Knoxville, TN
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $95–110
- Website
- New York to Tennessee Bus
- Adult One-way
- $95–110
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Greensboro Bus Stop to Asheville, NC
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $26–50
- Website
- Greyhound
Bus from Buffalo to Port Authority Bus Terminal
- Ave. Duration
- 8h 5m
- Frequency
- Every 3 hours
- Estimated price
- $60–120
- Website
- Greyhound
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Buffalo to Port Authority Bus Terminal
- Ave. Duration
- 8h 30m
- Frequency
- 3 times a day
- Estimated price
- $55–250
- Website
- Trailways
- Schedules at
- Trailways
- Saver
- $55–240
- Flexible
- $100–250
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from New York to Knoxville
- Ave. Duration
- 11h 45m
- Frequency
- Once daily
- Estimated price
- $95–140
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $95–140
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Buffalo to New York Midtown
- Ave. Duration
- 8h 35m
- Frequency
- Hourly
- Estimated price
- $70–130
- Schedules at
- Flixbus USA
- Ave. Duration
- 1h 8m
- Estimated price
- $170–230
Knoxville Taxi Service
- Phone
- +1 865 691 1900
Knoxville Taxi Service
- Phone
- +1 865 691 1900
Knoxville Taxi Service
- Phone
- +1 865 691 1900
Knoxville Taxi Service
- Phone
- +1 865 691 1900
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide















