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How to get fromBuffalo Depew Station to Ithacaby train, bus, car, or bus (Flixbus)

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There are 4 ways to get from Buffalo Depew Station to Ithaca by train, bus, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus via Rochester

    best
    1. Take the train from Buffalo Depew Station to Rochestertrain train Maple Leaf / ...
    2. Take the bus from Rochester to Ithacabus bus Adt N823 / ...
    3h 41m
    $36–209

  2. Drive 136.5 mi

    cheapest
    1. Drive from Buffalo Depew Station to Ithacacar car 136.5 mi
    3h 9m
    $25–36

  3. Train, bus

    1. Take the train from Buffalo Depew Station to Syracuse Regional Transportation Centertrain train Empire Service / ...
    2. Take the bus from Syracuse Bus Station to Ithacabus bus FlixBus 2691
    4h 14m
    $48–198

  4. Bus

    1. Take the bus from Buffalo to Ithacabus bus FlixBus 2685 / ...
    5h 52m
    $30–49

Buffalo Depew Station to Ithaca by train and bus

Calendar27Weekly Services
Duration3h 41mAverage Duration
Ticket$36Cheapest Price
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Questions & Answers

Map of how to get from Buffalo Depew Station to Ithaca.ExpandLaunch map view
  • Distance: 151.7 mi
  • Duration: 3h 41m

What companies run services between Buffalo Depew Station, NY, USA and Ithaca, NY, USA?

Flixbus USA operates a bus from Buffalo to Ithaca twice daily. Tickets cost $26–45 and the journey takes 3h 45m. FlixBus-us also services this route once daily.

Train operators
Bus operators

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