Rome2Rio

How to get fromBuffalo Depew Station to Jacksonvilleby plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or train

Find Transport to Jacksonville

See all options

There are 7 ways to get from Buffalo Depew Station to Jacksonville by plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Jacksonville

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Jacksonville (JAX)plane plane BUF - JAX
    5h 45m
    $145–670

  2. Bus

    1. Take the bus from Buffalo, NY to Youngstown, OHbus bus
    2. Take the bus from Youngstown Bus Stop to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Jacksonvillebus bus
    28h 12m
    $176–349

  3. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Cleveland Amtraktrain train Lake Shore Limited
    2. Take the train from Cleveland Amtrak to Jacksonvilletrain train Floridian
    33h 41m
    $441–925

  4. Drive 1,037.2 mi

    1. Drive from Buffalo Depew Station to Jacksonvillecar car 1,037.2 mi
    17h 30m
    $190–274

  5. Fly Buffalo Niagara International Airport to Brunswick Golden Isles Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Brunswick Golden Isles Airport (BQK)plane plane BUF - BQK
    2. Take the bus from Brunswick to Jacksonvillebus bus
    7h 20m
    $200–655

  6. Train to Rochester, fly to Jacksonville

    1. Take the train from Buffalo Depew Station to Rochestertrain train
    2. Fly from Rochester (ROC) to Jacksonville (JAX)plane plane ROC - JAX
    7h 49m
    $166–830

  7. Bus, train

    1. Take the bus from Buffalo, Ny to Pittsburgh, Pabus bus 530
    2. Take the train from Pittsburgh Amtrak Station to Jacksonvilletrain train Floridian
    36h 34m
    $395–977

Buffalo Depew Station to Jacksonville by bus

Calendar5Weekly Buses
Duration28h 12mAverage Duration
Ticket$176Cheapest Price
See schedules

Questions & Answers

Map of how to get from Buffalo Depew Station to Jacksonville.ExpandLaunch map view
  • Distance: 896.4 mi
  • Duration: 5h 45m

What companies run services between Buffalo Depew Station, NY, USA and Jacksonville, FL, USA?

Southwest Airlines, Delta, and three other airlines fly from Buffalo Niagara International Airport (BUF) to Jacksonville (JAX) hourly. Alternatively, you can take a bus from Dick Road & AMTRAK Station to Jacksonville via Walden Avenue & Thruway Transit Center, Buffalo, NY, Youngstown, OH, Youngstown Bus Stop, and Washington Union Station in around 28h 12m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers