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How to get fromBuffalo Depew Station to Lexingtonby plane, car, train, bus, or bus (Greyhound)

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There are 6 ways to get from Buffalo Depew Station to Lexington by plane, car, train, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Louisville International Airport, drive

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Louisville International Airport (SDF)plane plane BUF - SDF
    2. Drive from Louisville-Airport-SDF to Lexingtoncar car
    5h 27m
    $148–738

  2. Bus

    cheapest
    1. Take the bus from Buffalo, NY to Cincinnati, OHbus bus Buffalo
    2. Take the bus from Cincinnati Bus Station to Lexington Bus Stopbus bus Greyhound US0110 / ...
    14h 59m
    $89–158

  3. Train, bus

    1. Take the train from Buffalo Depew Station to Toledotrain train Lake Shore Limited
    2. Take the bus from Toledo Bus Stop to Lexington Bus Stopbus bus Greyhound US0110
    13h 51m
    $163–311

  4. Drive 522.3 mi

    1. Drive from Buffalo Depew Station to Lexingtoncar car 522.3 mi
    8h 56m
    $96–138

  5. Fly to Blue Grass Airport

    1. Fly from Buffalo Niagara International Airport (BUF) to Blue Grass Airport (LEX)plane plane BUF - LEX
    6h 15m
    $196–1,019

  6. Bus via Akron

    1. Take the bus from Buffalo to Akronbus bus
    2. Take the bus from Akron to Cincinnatibus bus
    3. Take the bus from Cincinnati Bus Station to Lexington Bus Stopbus bus
    15h 30m

Buffalo Niagara International Airport (BUF) to Louisville International Airport (SDF) flights

Calendar81Weekly Planes
Duration5h 35mAverage Duration
Ticket$127Cheapest Price
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Questions & Answers

Map of how to get from Buffalo Depew Station to Lexington.ExpandLaunch map view
  • Distance: 575.7 mi
  • Duration: 5h 27m

What companies run services between Buffalo Depew Station, NY, USA and Lexington, KY, USA?

Delta, American Airlines, and United Airlines fly from Buffalo Niagara International Airport (BUF) to Blue Grass Airport (LEX) hourly. Alternatively, you can take a bus from Dick Road & AMTRAK Station to Lexington via Walden Avenue & Thruway Transit Center, Buffalo, NY, Cincinnati, OH, Cincinnati Bus Station, and Lexington Bus Stop in around 14h 59m.

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