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How to get fromBuffalo Depew Station to Milwaukeeby plane, train (Amtrak), train, bus, or car

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There are 5 ways to get from Buffalo Depew Station to Milwaukee by plane, train (Amtrak), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to General Mitchell International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to General Mitchell International Airport (MKE)plane plane BUF - MKE
    3h 59m
    $127–670

  2. Drive 622.1 mi

    cheapest
    1. Drive from Buffalo Depew Station to Milwaukeecar car 622.1 mi
    10h 48m
    $114–164

  3. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to Milwaukeetrain train Hiawatha Service / ...
    13h 2m
    $199–407

  4. Train, bus

    1. Take the train from Buffalo to Toronto Union Stationtrain train
    2. Take the bus from Toronto to Detroit Bus Stationbus bus
    3. Take the bus from Detroit Bus Station to Milwaukee Intermodal Stationbus bus
    20h 44m
    $131–353

  5. Fly to Chicago O'Hare International Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)plane plane BUF - ORD
    2. Take the bus from Multi-Modal/Rental Car Facility to Milwaukee Intermodal/Amtrak Stationbus bus
    4h 44m
    $202–483

Buffalo Depew Station to Milwaukee by train (Amtrak)

Calendar14Weekly Trains
Duration13h 2mAverage Duration
Ticket$199Cheapest Price
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Questions & Answers

Map of how to get from Buffalo Depew Station to Milwaukee.ExpandLaunch map view
  • Distance: 474.1 mi
  • Duration: 3h 59m

What companies run services between Buffalo Depew Station, NY, USA and Milwaukee, WI, USA?

Southwest Airlines, Delta, and two other airlines fly from Buffalo Niagara International Airport (BUF) to General Mitchell International Airport (MKE) hourly. Alternatively, you can take a train from Buffalo Depew Station to Milwaukee via Chicago Union Station in around 13h 2m.

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