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How to get fromBuffalo Depew Station to Myrtle Beachby plane, train, bus, bus (Flixbus, Greyhound), or car

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There are 7 ways to get from Buffalo Depew Station to Myrtle Beach by plane, train, bus, bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR)plane plane BUF - MYR
    3h 59m
    $110–481

  2. Train, bus via New York

    1. Take the train from Buffalo Depew Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain train
    3. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    26h 33m
    $386–793

  3. Bus

    1. Take the bus from Buffalo to Newark Penn Stationbus bus
    2. Take the bus from Newark Penn Station to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Wilmington Cape Fear Public Transitbus bus
    4. Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus bus
    26h 52m
    $168–332

  4. Drive 763.1 mi

    1. Drive from Buffalo Depew Station to Myrtle Beachcar car 763.1 mi
    15h 32m
    $140–202

  5. Train to Rochester, fly

    1. Take the train from Buffalo Depew Station to Rochestertrain train
    2. Fly from Rochester (ROC) to Myrtle Beach (MYR)plane plane ROC - MYR
    4h 4m
    $226–891

  6. Train, bus

    1. Take the train from Buffalo Depew Station to Cleveland Amtraktrain train
    2. Take the train from Cleveland Amtrak to Raleigh Union Stationtrain train
    3. Take the bus from Raleigh Bus Station to Myrtle Beach Bus Stationbus bus
    33h 44m
    $358–755

  7. Bus, train

    1. Take the bus from Buffalo, Ny to Pittsburgh, Pabus bus 530
    2. Take the train from Pittsburgh Amtrak Station to Raleigh Union Stationtrain train
    3. Take the bus from Raleigh Bus Station to Myrtle Beach Bus Stationbus bus
    36h 37m
    $311–766

Buffalo Depew Station to Myrtle Beach by train and bus

Calendar14Weekly Services
Duration26h 33mAverage Duration
Ticket$386Cheapest Price
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Questions & Answers

Map of how to get from Buffalo Depew Station to Myrtle Beach.ExpandLaunch map view
  • Distance: 645.7 mi
  • Duration: 3h 59m

What companies run services between Buffalo Depew Station, NY, USA and Myrtle Beach, SC, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR) every 2 hours. Alternatively, you can take a bus from Dick Road & AMTRAK Station to Myrtle Beach Bus Station via Walden Avenue & Thruway Transit Center, Buffalo, Newark Penn Station, Raleigh Bus Station, and Wilmington Cape Fear Public Transit in around 26h 52m.

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