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How to get fromBuffalo Depew Station to Mysticby plane, train, train (Amtrak), bus, or car

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There are 10 ways to get from Buffalo Depew Station to Mystic by plane, train, train (Amtrak), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Boston Logan Airport, train

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    2. Take the train from Boston to Mystic Stationtrain train
    4h 26m
    $123–511

  2. Drive 434 mi

    cheapest
    1. Drive from Buffalo Depew Station to Mysticcar car 434 mi
    7h 59m
    $80–115

  3. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Mystic Stationtrain train Northeast Regional
    11h 43m
    $179–374

  4. Bus, train

    1. Take the bus from Buffalo to Bostonbus bus Greyhound US0171
    2. Take the train from Boston to Mystic Stationtrain train Northeast Regional
    14h 40m
    $104–209

  5. Fly Buffalo Niagara International Airport to Laguardia Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Laguardia Airport (LGA)plane plane BUF - LGA
    2. Take the train from 125th Street - Harlem to Stamfordtrain train
    3. Take the train from Stamford Amtrak Station to Mystic Stationtrain train
    5h 56m
    $142–712

  6. Fly Buffalo Niagara International Airport to John F. Kennedy International Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to John F. Kennedy International Airport (JFK)plane plane BUF - JFK
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Mystic Stationtrain train
    5h 53m
    $118–466

  7. Fly Buffalo Niagara International Airport to Newark Liberty International Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Newark Liberty International Airport (EWR)plane plane BUF - EWR
    2. Take the train from Newark Liberty International Airport to Mystic Stationtrain train
    6h 17m
    $109–447

  8. Train to Rochester, fly to Boston Logan Airport, train

    1. Take the train from Buffalo Depew Station to Rochestertrain train
    2. Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane plane ROC - BOS
    3. Take the train from Boston to Mystic Stationtrain train
    6h 22m
    $139–651

  9. Train via New York

    1. Take the train from Buffalo to New York Penn Stationtrain train VIA Rail
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Mystic Stationtrain train Northeast Regional
    12h 29m
    $157–371

  10. Train #2 (Amtrak)

    1. Take the train from Buffalo Depew Station to Bostontrain train Lake Shore Limited
    2. Take the train from Boston to Mystic Stationtrain train Northeast Regional
    13h 41m
    $187–386

Buffalo Depew Station to Mystic by train (Amtrak)

Calendar28Weekly Trains
Duration11h 43mAverage Duration
Ticket$179Cheapest Price
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Questions & Answers

Map of how to get from Buffalo Depew Station to Mystic.ExpandLaunch map view
  • Distance: 502.9 mi
  • Duration: 4h 26m

What companies run services between Buffalo Depew Station, NY, USA and Mystic, CT, USA?

You can take a train from Buffalo Depew Station to Mystic Station via Ny Moynihan Train Hall At Penn Station in around 11h 43m.

Airlines
Train operators
Bus operators

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