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How to get fromBuffalo Depew Station to New Orleansby plane, train (Amtrak), bus (Flixbus, Greyhound), car, or train

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There are 7 ways to get from Buffalo Depew Station to New Orleans by plane, train (Amtrak), bus (Flixbus, Greyhound), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Louis Armstrong New Orleans International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Louis Armstrong New Orleans International Airport (MSY)plane plane BUF - MSY
    5h 52m
    $225–770

  2. Fly Buffalo Niagara International Airport to Gulfport-Biloxi Regional Airport, train

    cheapest
    1. Fly from Buffalo Niagara International Airport (BUF) to Gulfport-Biloxi Regional Airport (GPT)plane plane BUF - GPT
    2. Take the train from Gulfport, MS to New Orleans, LA - Union Passenger Terminaltrain train
    8h 45m
    $202–833

  3. Train via Chicago (Amtrak)

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain train City of New Orleans
    31h 15m
    $458–996

  4. Bus

    1. Take the bus from Buffalo to New York Midtownbus bus
    2. Take the bus from New York Midtown to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to New Orleans Bus Stationbus bus
    39h 50m
    $294–524

  5. Drive 1,237.2 mi

    1. Drive from Buffalo Depew Station to New Orleanscar car 1,237.2 mi
    20h 28m
    $226–327

  6. Train to Rochester, fly to Louis Armstrong New Orleans International Airport

    1. Take the train from Buffalo Depew Station to Rochestertrain train
    2. Fly from Rochester (ROC) to Louis Armstrong New Orleans International Airport (MSY)plane plane ROC - MSY
    7h 46m
    $247–1,131

  7. Train

    1. Take the train from Buffalo to New York Penn Stationtrain train VIA Rail
    2. Take the train from Ny Moynihan Train Hall At Penn Station to New Orleans Union Passenger Terminaltrain train Crescent
    41h 58m
    $548–1,233

Buffalo Depew Station to New Orleans by train (Amtrak)

Calendar7Weekly Trains
Duration31h 15mAverage Duration
Ticket$458Cheapest Price
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Questions & Answers

Map of how to get from Buffalo Depew Station to New Orleans.ExpandLaunch map view
  • Distance: 1,114.1 mi
  • Duration: 5h 52m

What companies run services between Buffalo Depew Station, NY, USA and New Orleans, LA, USA?

Delta, Southwest Airlines, and three other airlines fly from Buffalo Niagara International Airport (BUF) to Louis Armstrong New Orleans International Airport (MSY) every 2 hours. Alternatively, you can take a train from Buffalo Depew Station to New Orleans Union Passenger Terminal via Chicago Union Station in around 31h 15m.

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