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How to get fromBuffalo Depew Station to Pittsburghby bus (Greyhound), train (Amtrak), car, plane, or bus

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There are 5 ways to get from Buffalo Depew Station to Pittsburgh by bus (Greyhound), train (Amtrak), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Youngstown

    best
    1. Take the bus from Buffalo, NY to Youngstown, OHbus bus Buffalo
    2. Take the bus from Youngstown Bus Stop to Pittsburgh Intermodal Stationbus bus Greyhound US0164
    7h 17m
    $31–79

  2. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Cleveland Amtraktrain train Lake Shore Limited
    2. Take the train from Cleveland Amtrak to Pittsburgh Amtrak Stationtrain train Floridian
    7h 25m
    $106–218

  3. Drive 218.4 mi

    1. Drive from Buffalo Depew Station to Pittsburghcar car 218.4 mi
    3h 47m
    $40–58

  4. Fly

    1. Fly from Buffalo Niagara International Airport (BUF) to Pittsburgh International Airport (PIT)plane plane BUF - PIT
    4h 51m
    $104–567

  5. Bus

    1. Take the bus from Buffalo to Pittsburghbus bus Fab530 / ...
    9h 37m
    $104–194

Buffalo Depew Station to Pittsburgh by bus

Calendar14Weekly Buses
Duration7h 17mAverage Duration
Ticket$31Cheapest Price
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Questions & Answers

Map of how to get from Buffalo Depew Station to Pittsburgh.ExpandLaunch map view
  • Distance: 256.1 mi
  • Duration: 7h 17m

What companies run services between Buffalo Depew Station, NY, USA and Pittsburgh, PA, USA?

You can take a bus from Dick Road & AMTRAK Station to Pittsburgh Intermodal Station via Walden Avenue & Thruway Transit Center, Buffalo, NY, Youngstown, OH, and Youngstown Bus Stop in around 7h 17m. Alternatively, you can take a train from Buffalo Depew Station to Pittsburgh Amtrak Station via Cleveland Amtrak in around 7h 25m.

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