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How to get fromBuffalo Depew Station to Portlandby plane, train, bus, bus (Greyhound, Amtrak), car, or bus (Flixbus, Amtrak)

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There are 7 ways to get from Buffalo Depew Station to Portland by plane, train, bus, bus (Greyhound, Amtrak), car, or bus (Flixbus, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Portland

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Portland (PWM)plane plane BUF - PWM
    3h 42m
    $114–567

  2. Fly to Augusta State Airport, bus

    cheapest
    1. Fly from Buffalo Niagara International Airport (BUF) to Augusta State Airport (AUG)plane plane BUF - AUG
    2. Take the bus from Augusta Transportation Center to Portland Transportation Centerbus bus
    6h 16m
    $88–352

  3. Train, bus

    1. Take the train from Buffalo Depew Station to Bostontrain train Lake Shore Limited
    2. Take the bus from Boston, MA - South Station to Portland, MEbus bus Logan Airport / ...
    13h 42m
    $175–366

  4. Bus

    1. Take the bus from Buffalo to Bostonbus bus Greyhound US0171
    2. Take the bus from Boston, MA - South Station to Portland, MEbus bus Logan Airport / ...
    14h 27m
    $95–189

  5. Drive 501.6 mi

    1. Drive from Buffalo Depew Station to Portlandcar car 501.6 mi
    10h 15m
    $92–133

  6. Fly to Boston Logan Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    2. Take the bus from Logan International Airport to Portland, MEbus bus
    4h 17m
    $106–467

  7. Bus via Ithaca

    1. Take the bus from Buffalo to Ithacabus bus
    2. Take the bus from Ithaca to Bostonbus bus
    3. Take the bus from Boston, MA - South Station to Portland, MEbus bus
    17h 2m
    $105–194

Buffalo Depew Station to Portland by train and bus

Calendar7Weekly Services
Duration13h 42mAverage Duration
Ticket$175Cheapest Price
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Questions & Answers

Map of how to get from Buffalo Depew Station to Portland.ExpandLaunch map view
  • Distance: 429.8 mi
  • Duration: 3h 42m

What companies run services between Buffalo Depew Station, NY, USA and Portland, ME, USA?

Southwest Airlines, Delta, and three other airlines fly from Buffalo Niagara International Airport (BUF) to Portland (PWM) hourly. Alternatively, you can take a bus from Dick Road & AMTRAK Station to Portland, ME via Walden Avenue & Thruway Transit Center, Buffalo, Boston, and Boston, MA - South Station in around 14h 27m.

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