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How to get fromBuffalo Depew Station to Roanokeby plane, train (Amtrak), bus (Flixbus, Greyhound), car, train, or bus (Greyhound, Flixbus)

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There are 6 ways to get from Buffalo Depew Station to Roanoke by plane, train (Amtrak), bus (Flixbus, Greyhound), car, train, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Roanoke Regional Airport-Woodrum Field (ROA)plane plane BUF - ROA
    4h 53m
    $98–482

  2. Drive 491.5 mi

    cheapest
    1. Drive from Buffalo Depew Station to Roanokecar car 491.5 mi
    9h 54m
    $90–130

  3. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Roanoketrain train Northeast Regional
    18h 33m
    $279–584

  4. Bus via Newark

    1. Take the bus from Buffalo to Newark Penn Stationbus bus
    2. Take the bus from Newark Penn Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Roanoke Bus Stopbus bus
    22h 6m
    $129–259

  5. Train to Rochester, fly

    1. Take the train from Buffalo Depew Station to Rochestertrain train
    2. Fly from Rochester (ROC) to Roanoke Regional Airport-Woodrum Field (ROA)plane plane ROC - ROA
    6h 48m
    $114–632

  6. Bus

    1. Take the bus from Buffalo, Ny to Pittsburgh, Pabus bus 530
    2. Take the bus from Pittsburgh Intermodal Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Salem VDOT Park & Ridebus bus
    23h
    $125–348

Buffalo Depew Station to Roanoke by train (Amtrak)

Calendar7Weekly Trains
Duration18h 33mAverage Duration
Ticket$279Cheapest Price
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Questions & Answers

Map of how to get from Buffalo Depew Station to Roanoke.ExpandLaunch map view
  • Distance: 404.2 mi
  • Duration: 4h 53m

What companies run services between Buffalo Depew Station, NY, USA and Roanoke, VA, USA?

United Airlines, American Airlines, and Delta fly from Buffalo Niagara International Airport (BUF) to Roanoke Regional Airport-Woodrum Field (ROA) hourly. Alternatively, you can take a train from Buffalo Depew Station to Roanoke via Ny Moynihan Train Hall At Penn Station in around 18h 33m.

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