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How to get fromBuffalo Depew Station to San Antonioby plane, train, bus, train (Amtrak), car, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Buffalo Depew Station to San Antonio by plane, train, bus, train (Amtrak), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to San Antonio International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to San Antonio International Airport (SAT)plane plane BUF - SAT
    5h 58m
    $246–1,019

  2. Train, bus

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the bus from Chicago to Tornado Bus Co - San Antoniobus bus Chicago
    36h 57m
    $351–690

  3. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to San Antonio Stationtrain train Texas Eagle
    44h 9m
    $566–1,245

  4. Drive 1,628.3 mi

    1. Drive from Buffalo Depew Station to San Antoniocar car 1,628.3 mi
    26h 49m
    $298–430

  5. Train to Rochester, fly to San Antonio International Airport

    1. Take the train from Buffalo Depew Station to Rochestertrain train
    2. Fly from Rochester (ROC) to San Antonio International Airport (SAT)plane plane ROC - SAT
    8h 5m
    $268–1,180

  6. Fly Buffalo Niagara International Airport to Austin-Bergstrom International Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Austin-Bergstrom International Airport (AUS)plane plane BUF - AUS
    2. Take the bus from Austin Eastside Bus Plaza to San Antonio Bus Stationbus bus
    8h 34m
    $247–1,044

  7. Bus

    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Dallas Bus Stationbus bus
    4. Take the bus from Dallas Bus Station to San Antonio Bus Stationbus bus
    40h 12m
    $254–504

Buffalo Depew Station to San Antonio by train and bus

Calendar7Weekly Services
Duration36h 57mAverage Duration
Ticket$351Cheapest Price
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Questions & Answers

Map of how to get from Buffalo Depew Station to San Antonio.ExpandLaunch map view
  • Distance: 1,444.1 mi
  • Duration: 5h 58m

What companies run services between Buffalo Depew Station, NY, USA and San Antonio, TX, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to San Antonio International Airport (SAT) hourly. Alternatively, you can take a train from Buffalo Depew Station to San Antonio Station via Chicago Union Station in around 44h 9m.

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