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How to get fromBuffalo to Bryson Cityby plane, car, train, or bus

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There are 10 ways to get from Buffalo to Bryson City by plane, car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Asheville Regional Airport, drive

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Asheville Regional Airport (AVL)plane plane BUF - AVL
    2. Drive from Asheville-Airport-AVL to Bryson Citycar car
    6h 59m
    $78–379

  2. Train, bus, drive

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    3. Drive from Knoxville, TN to Bryson Citycar car
    24h 9m
    $353–504

  3. Train, bus, drive via Greensboro

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Greensborotrain train
    3. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    4. Drive from Asheville, NC to Bryson Citycar car
    25h 18m
    $561–866

  4. Drive  733.6 mi

    1. Drive from Buffalo to Bryson Citycar car 733.6 mi
    12h 57m
    $122–175

  5. Fly to Mcghee Tyson Airport, drive

    1. Fly from Buffalo Niagara International Airport (BUF) to Mcghee Tyson Airport (TYS)plane plane BUF - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Bryson Citycar car
    7h 46m
    $195–1,022

  6. Fly to Greenville–Spartanburg International Airport, drive

    1. Fly from Buffalo Niagara International Airport (BUF) to Greenville–Spartanburg International Airport (GSP)plane plane BUF - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Bryson Citycar car
    7h 44m
    $107–501

  7. Fly to Hartsfield-Jackson Atlanta International Airport, drive

    1. Fly from Buffalo Niagara International Airport (BUF) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane BUF - ATL
    2. Drive from Atlanta-Airport-ATL to Bryson Citycar car
    6h 59m
    $79–312

  8. Bus, drive

    1. Take the bus from Buffalo to New York Midtownbus bus
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    3. Drive from Knoxville, TN to Bryson Citycar car
    24h 21m
    $180–233

  9. Train, bus, drive via Farragut

    1. Take the train from Buffalo to New York Penn Stationtrain train
    2. Take the bus from New York to Knoxvillebus bus Nyc
    3. Drive from Knoxville to Bryson Citycar car
    24h 37m
    $229–443

  10. Bus, train, drive

    1. Take the bus from Buffalo, Ny to Pittsburgh, Pabus bus 530
    2. Take the train from Pittsburgh Amtrak Station to Carytrain train
    3. Take the train from Cary to Greensborotrain train
    4. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    5. Drive from Asheville, NC to Bryson Citycar car
    31h 8m
    $461–894

Buffalo Niagara International Airport (BUF) to Asheville Regional Airport (AVL) flights

Calendar76Weekly Planes
Duration5h 26mAverage Duration
Ticket$65Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Bryson City.ExpandLaunch map view
  • Distance: 638.7 mi
  • Duration: 6h 59m

What companies run services between Buffalo, NY, USA and Bryson City, NC, USA?

There is no direct connection from Buffalo to Bryson City. However, you can take the line 24 bus to Genesee Street & 4219 Genesee Street, walk to Buffalo Niagara International Airport (BUF) airport, fly to Asheville Regional Airport (AVL), then drive to Bryson City. Alternatively, you can take a train from Buffalo to Bryson City via Ny Moynihan Train Hall At Penn Station, 34 St-Herald Sq, East Broadway, New York, NY, and Knoxville, TN in around 24h 9m.

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