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How to get fromBuffalo to Cambridgeby plane, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)

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There are 6 ways to get from Buffalo to Cambridge by plane, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    3h 6m
    $85–457

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Buffalo to Bostonbus bus Greyhound US0171
    10h 5m
    $70–140

  3. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Bostontrain train Lake Shore Limited
    12h 36m
    $152–466

  4. Drive 452.5 mi

    1. Drive from Buffalo to Cambridgecar car 452.5 mi
    7h 55m
    $83–120

  5. Bus to Rochester, fly

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane plane ROC - BOS
    4h 39m
    $104–454

  6. Bus via Ithaca (Flixbus)

    1. Take the bus from Buffalo to Ithacabus bus FlixBus 2685 / ...
    2. Take the bus from Ithaca to Bostonbus bus FlixBus 2691
    12h 53m
    $90–157

Buffalo to Cambridge by bus (Greyhound)

Calendar7Weekly Buses
Duration10h 5mAverage Duration
Ticket$70Cheapest Price
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Questions & Answers

Map of how to get from Buffalo to Cambridge.ExpandLaunch map view
  • Distance: 415 mi
  • Duration: 3h 6m

What companies run services between Buffalo, NY, USA and Cambridge, MA, USA?

American Airlines, JetBlue Airways, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS) every 4 hours. Alternatively, Greyhound USA operates a bus from Buffalo to Boston once daily. Tickets cost $70–140 and the journey takes 10h 5m.

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