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How to get fromBuffalo to Charlestonby plane, train (Amtrak), car, bus, shuttle, or train

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There are 6 ways to get from Buffalo to Charleston by plane, train (Amtrak), car, bus, shuttle, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Charleston International Airport (CHS)plane plane BUF - CHS
    6h 29m
    $114–630

  2. Train (Amtrak)

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    23h 48m
    $403–806

  3. Drive 859.4 mi

    1. Drive from Buffalo to Charlestoncar car 859.4 mi
    14h 42m
    $157–227

  4. Bus to Rochester, fly

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Charleston International Airport (CHS)plane plane ROC - CHS
    6h 5m
    $172–797

  5. Shuttle to Toronto Pearson International Airport, fly

    1. Take a shuttle bus from Buffalo Airport to Pearson International Airport Terminal 1shuttle bus
    2. Fly from Toronto Pearson International Airport (YYZ) to Charleston International Airport (CHS)plane plane YYZ - CHS
    8h 58m
    $169–504

  6. Bus, train

    1. Take the bus from Buffalo to Newark Penn Stationbus bus FlixBus N2686 / ...
    2. Take the train from Newark Penn Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    24h 34m
    $298–595

Buffalo to Charleston by bus and train

Calendar14Weekly Services
Duration24h 34mAverage Duration
Ticket$298Cheapest Price
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Questions & Answers

Map of how to get from Buffalo to Charleston.ExpandLaunch map view
  • Distance: 722.8 mi
  • Duration: 6h 29m

What companies run services between Buffalo, NY, USA and Charleston, SC, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Charleston International Airport (CHS) hourly. Alternatively, you can take a train from Buffalo to Charleston via Ny Moynihan Train Hall At Penn Station and Charleston Amtrak Station in around 23h 48m.

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