Rome2Rio

How to get fromBuffalo to Charlestonby plane, train (Amtrak), car, bus, or train

Find Transport to Charleston

See all options

There are 7 ways to get from Buffalo to Charleston by plane, train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Charleston International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Charleston International Airport (CHS)plane plane BUF - CHS
    6h 49m
    $99–554

  2. Train (Amtrak)

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    23h 48m
    $671–1,060

  3. Drive  859.4 mi

    1. Drive from Buffalo to Charlestoncar car 859.4 mi
    14h 42m
    $157–227

  4. Bus to Rochester, fly to Charleston International Airport

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Charleston International Airport (CHS)plane plane ROC - CHS
    6h 32m
    $152–745

  5. Fly Buffalo Niagara International Airport to Hilton Head Airport, drive

    1. Fly from Buffalo Niagara International Airport (BUF) to Hilton Head Airport (HHH)plane plane BUF - HHH
    2. Drive from Hilton Head Airport (HHH) to Charlestoncar car
    7h 57m
    $100–459

  6. Bus to Toronto Pearson International Airport, fly to Charleston International Airport

    1. Take the bus from Buffalo to Mississaugabus bus
    2. Fly from Toronto Pearson International Airport (YYZ) to Charleston International Airport (CHS)plane plane YYZ - CHS
    8h 56m
    $108–511

  7. Bus, train

    1. Take the bus from Buffalo to Newark Penn Stationbus bus FlixBus N2686 / ...
    2. Take the train from Newark Penn Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    24h 32m
    $458–761

Buffalo to Charleston by bus and train

Calendar14Weekly Services
Duration24h 32mAverage Duration
Ticket$458Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Buffalo to Charleston.ExpandLaunch map view
  • Distance: 724.6 mi
  • Duration: 6h 49m

What companies run services between Buffalo, NY, USA and Charleston, SC, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Charleston International Airport (CHS) every 2 hours. Alternatively, you can take a train from Buffalo to Charleston via Ny Moynihan Train Hall At Penn Station and Charleston Amtrak Station in around 23h 48m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There