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How to get fromBuffalo to Charlotteby plane, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)

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There are 6 ways to get from Buffalo to Charlotte by plane, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Charlotte Douglas International Airport (CLT)plane plane BUF - CLT
    4h 9m
    $100–555

  2. Bus via Charleston

    cheapest
    1. Take the bus from Buffalo, NY to Robert K Pfaff Transit Center - Akronbus bus
    2. Take the bus from Robert K Pfaff Transit Center - Akron to Charleston, WVbus bus
    3. Take the bus from Charleston, WV to Charlotte Bus Stationbus bus
    15h 40m
    $83–196

  3. Train (Amtrak)

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Charlotte Amtrak Stationtrain train Crescent / ...
    21h 47m
    $248–606

  4. Drive  654.5 mi

    1. Drive from Buffalo to Charlottecar car 654.5 mi
    11h 11m
    $120–173

  5. Bus to Rochester, fly

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Charlotte Douglas International Airport (CLT)plane plane ROC - CLT
    5h 16m
    $162–844

  6. Bus

    1. Take the bus from Buffalo to Columbusbus bus FlixBus 2526
    2. Take the bus from Columbus to Charlottebus bus Bsb 32
    19h 2m
    $96–177

Buffalo to Charlotte by bus

Calendar7Weekly Buses
Duration15h 40mAverage Duration
Ticket$83Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Charlotte.ExpandLaunch map view
  • Distance: 565.8 mi
  • Duration: 4h 9m

What companies run services between Buffalo, NY, USA and Charlotte, NC, USA?

American Airlines, Southwest Airlines, and United Airlines fly from Buffalo Niagara International Airport (BUF) to Charlotte Douglas International Airport (CLT) every 2 hours. Alternatively, you can take a bus from Buffalo, NY to Charlotte Bus Station via Robert K Pfaff Transit Center - Akron and Charleston, WV in around 15h 40m.

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Want to know more about travelling around United States

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Need to know: Greyhound

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