Rome2Rio

How to get fromBuffalo to Charlotteby plane, bus, train (Amtrak), car, or bus (Flixbus, Greyhound)

Find Transport to Charlotte

See all options

There are 7 ways to get from Buffalo to Charlotte by plane, bus, train (Amtrak), car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Charlotte Douglas International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Charlotte Douglas International Airport (CLT)plane plane BUF - CLT
    4h 10m
    $105–655

  2. Bus via Charleston

    cheapest
    1. Take the bus from Buffalo to Akronbus bus
    2. Take the bus from Akron to Charlestonbus bus
    3. Take the bus from Charleston to Charlottebus bus
    15h 40m
    $69–196

  3. Train (Amtrak)

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Charlotte Amtrak Stationtrain train Crescent / ...
    21h 47m
    $571–920

  4. Drive  654.5 mi

    1. Drive from Buffalo to Charlottecar car 654.5 mi
    11h 11m
    $120–173

  5. Bus to Rochester, fly to Charlotte Douglas International Airport

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Charlotte Douglas International Airport (CLT)plane plane ROC - CLT
    5h 24m
    $173–896

  6. Bus to Rochester, fly to Concord

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Concord (USA)plane plane ROC - USA
    5h 18m
    $283–941

  7. Bus

    1. Take the bus from Buffalo to Columbusbus bus FlixBus 2526
    2. Take the bus from Columbus to Charlotte Bus Stationbus bus Greyhound US0140
    18h 33m
    $140–221

Buffalo to Charlotte by bus

Calendar7Weekly Buses
Duration15h 40mAverage Duration
Ticket$69Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Buffalo to Charlotte.ExpandLaunch map view
  • Distance: 565.8 mi
  • Duration: 4h 10m

What companies run services between Buffalo, NY, USA and Charlotte, NC, USA?

American Airlines, Southwest Airlines, and United Airlines fly from Buffalo Niagara International Airport (BUF) to Charlotte Douglas International Airport (CLT) every 3 hours. Alternatively, you can take a bus from Buffalo to Charlotte via Akron and Charleston in around 15h 40m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There