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How to get fromBuffalo to Charlotte, NCby plane, bus, train (Amtrak), car, or bus (Flixbus, Greyhound)

Find Transport to Charlotte, NC

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There are 7 ways to get from Buffalo to Charlotte, NC by plane, bus, train (Amtrak), car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Charlotte Douglas International Airport, line 8 bus

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Charlotte Douglas International Airport (CLT)plane plane BUF - CLT
    2. Take the bus from Transit Center- Bay F to Tuckaseegee Rd & Hazel Stbus bus
    4h 59m
    $106–658

  2. Bus via Charleston

    cheapest
    1. Take the bus from Buffalo to Akronbus bus
    2. Take the bus from Akron to Charlestonbus bus
    3. Take the bus from Charleston to Charlottebus bus
    16h 26m
    $70–199

  3. Train (Amtrak)

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Charlotte Amtrak Stationtrain train Crescent / ...
    22h 58m
    $575–926

  4. Drive  653.6 mi

    1. Drive from Buffalo to Charlotte, NCcar car 653.6 mi
    11h 10m
    $120–173

  5. Bus to Rochester, fly to Concord

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Concord (USA)plane plane ROC - USA
    4h 45m
    $315–978

  6. Bus to Rochester, fly to Charlotte Douglas International Airport

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Charlotte Douglas International Airport (CLT)plane plane ROC - CLT
    6h 12m
    $174–899

  7. Bus

    1. Take the bus from Buffalo to Columbusbus bus FlixBus 2526
    2. Take the bus from Columbus to Charlotte Bus Stationbus bus Greyhound US0140
    19h 40m
    $141–224

Buffalo to Charlotte, NC by bus and foot

Calendar7Weekly Services
Duration16h 26mAverage Duration
Ticket$70Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Charlotte, NC.ExpandLaunch map view
  • Distance: 570 mi
  • Duration: 4h 59m

What companies run services between Buffalo, NY, USA and Charlotte, NC, USA?

You can take a bus from Buffalo to Charlotte, NC via Akron, Charleston, Charlotte, 4th St & Graham St, and Tuckaseegee Rd & Hazel St in around 16h 26m. Alternatively, you can take a train from Buffalo to Charlotte, NC via Ny Moynihan Train Hall At Penn Station, Charlotte Amtrak Station, Parkwood Station, CTC Station, Transit Center- Bay F, and Tuckaseegee Rd & Glenwood Dr in around 22h 58m.

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