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How to get fromBuffalo to Charlotte, NCby plane, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus, Greyhound)

Find Transport to Charlotte, NC

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There are 7 ways to get from Buffalo to Charlotte, NC by plane, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Charlotte Douglas International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Charlotte Douglas International Airport (CLT)plane plane BUF - CLT
    4h 57m
    $102–611

  2. Bus

    cheapest
    1. Take the bus from Buffalo to Akronbus bus
    2. Take the bus from Akron to Charlestonbus bus
    3. Take the bus from Charleston to Charlottebus bus
    16h 24m
    $84–199

  3. Train (Amtrak)

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Charlotte Amtrak Stationtrain train Crescent / ...
    22h 56m
    $577–928

  4. Drive  653.6 mi

    1. Drive from Buffalo to Charlotte, NCcar car 653.6 mi
    11h 10m
    $120–173

  5. Bus to Rochester, fly to Concord

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Concord (USA)plane plane ROC - USA
    4h 45m
    $334–1,027

  6. Bus to Rochester, fly to Charlotte Douglas International Airport

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Charlotte Douglas International Airport (CLT)plane plane ROC - CLT
    6h 11m
    $164–851

  7. Bus via Newark

    1. Take the bus from Buffalo to Newark Penn Stationbus bus FlixBus N2686 / ...
    2. Take the bus from Newark Penn Station to Charlotte Bus Stationbus bus Greyhound US0700 / ...
    22h 4m
    $151–265

Buffalo to Charlotte, NC by bus and foot

Calendar7Weekly Services
Duration16h 24mAverage Duration
Ticket$84Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Charlotte, NC.ExpandLaunch map view
  • Distance: 569.9 mi
  • Duration: 4h 57m

What companies run services between Buffalo, NY, USA and Charlotte, NC, USA?

American Airlines, Southwest Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Charlotte Douglas International Airport (CLT) every 3 hours. Alternatively, you can take a bus from Buffalo to Charlotte, NC via Akron, Charleston, Charlotte, 4th St & Graham St, and Tuckaseegee Rd & Hazel St in around 16h 24m.

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Need to know: Greyhound

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