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How to get fromBuffalo to Charltonby bus (Greyhound, Flixbus), train (Amtrak), car, plane, train, bus (Flixbus), or bus

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There are 8 ways to get from Buffalo to Charlton by bus (Greyhound, Flixbus), train (Amtrak), car, plane, train, bus (Flixbus), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Buffalo to Springfield Union Stationbus bus Greyhound US0171
    2. Take the bus from Springfield Union Station to Worcester Union Stationbus bus Greyhound US0230 / ...
    11h 33m
    $67–127

  2. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Worcester Union Stationtrain train Lake Shore Limited
    13h 15m
    $144–438

  3. Drive 406 mi

    1. Drive from Buffalo to Charltoncar car 406 mi
    7h 6m
    $75–107

  4. Fly Buffalo Niagara International Airport to Boston Logan Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    2. Take the train from Lansdowne to Worcestertrain train
    7h 12m
    $94–474

  5. Bus via Ithaca (Flixbus)

    1. Take the bus from Buffalo to Ithacabus bus
    2. Take the bus from Ithaca to Albany Bus Terminal, NYbus bus
    3. Take the bus from Albany Bus Terminal, NY to Worcester Union Stationbus bus
    14h 23m
    $80–146

  6. Bus to Rochester, fly to Boston Logan Airport, train

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane plane ROC - BOS
    3. Take the train from Lansdowne to Worcestertrain train
    8h 44m
    $113–471

  7. Fly Buffalo Niagara International Airport to Laguardia Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Laguardia Airport (LGA)plane plane BUF - LGA
    2. Take the bus from New York, NY - 1st Avenue between East 38th and 39th Streets to Worcester, MA - Union Stationbus bus
    9h 24m
    $151–763

  8. Fly Buffalo Niagara International Airport to John F. Kennedy International Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to John F. Kennedy International Airport (JFK)plane plane BUF - JFK
    2. Take the bus from New York, NY - 1st Avenue between East 38th and 39th Streets to Worcester, MA - Union Stationbus bus
    9h 30m
    $127–518

Buffalo to Charlton by bus

Calendar7Weekly Buses
Duration11h 33mAverage Duration
Ticket$67Cheapest Price
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Questions & Answers

Map of how to get from Buffalo to Charlton.ExpandLaunch map view
  • Distance: 446.8 mi
  • Duration: 11h 33m

What companies run services between Buffalo, NY, USA and Charlton, MA, USA?

You can take a bus from Buffalo to Rt 20 and Northside Rd via Springfield Union Station, Worcester Union Station, and Central Hub in around 11h 33m. Alternatively, Amtrak operates a train from Buffalo Depew Station to Worcester Union Station once daily. Tickets cost $140–300 and the journey takes 10h 25m.

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