There are 6 ways to get from Buffalo to Chicago Union Station by plane, bus (Greyhound), train (Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Buffalo Niagara International Airport to Chicago Midway International Airport
best- Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane BUF - MDW
3h 36m$104–463Bus (Greyhound)
cheapest- Take the bus from Buffalo to Cleveland Bus Stationbus Greyhound US0171 / ...
- Take the bus from Cleveland Bus Station to Chicago Bus Stationbus Greyhound US0164
11h 49m$82–170Train (Amtrak)
- Take the train from Buffalo Depew Station to Chicago Union Stationtrain Lake Shore Limited
11h 50m$172–485Drive 531.3 mi
- Drive from Buffalo to Chicago Union Stationcar 531.3 mi
9h 3m$97–141Fly Buffalo Niagara International Airport to Chicago O'Hare International Airport
- Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)plane BUF - ORD
4h 2m$154–403Bus to Rochester, fly to Chicago Midway International Airport
- Take the bus from Buffalo to Rochester Bus Stopbus
- Fly from Rochester (ROC) to Chicago Midway International Airport (MDW)plane ROC - MDW
4h 55m$112–490
Buffalo to Chicago Union Station by bus and foot (Greyhound)
Questions & Answers
The cheapest way to get from Buffalo to Chicago Union Station is to bus which costs $80 - $170 and takes 11h 49m.
The fastest way to get from Buffalo to Chicago Union Station is to fly which takes 3h 36m and costs $100 - $470.
No, there is no direct bus from Buffalo to Chicago Union Station station. However, there are services departing from Buffalo and arriving at Chicago Bus Station via Cleveland Bus Station. The journey, including transfers, takes approximately 11h 49m.
No, there is no direct train from Buffalo to Chicago Union Station station. However, there are services departing from Buffalo and arriving at Chicago Union Station via Buffalo Depew Station. The journey, including transfers, takes approximately 11h 50m.
The distance between Buffalo and Chicago Union Station is 492 miles. The road distance is 534.4 miles.
The best way to get from Buffalo to Chicago Union Station without a car is to bus which takes 11h 49m and costs $80 - $170.
It takes approximately 3h 36m to get from Buffalo to Chicago Union Station, including transfers.
Buffalo to Chicago Union Station bus services, operated by Greyhound USA, depart from Buffalo station.
Buffalo to Chicago Union Station train services, operated by Amtrak, depart from Buffalo Depew Station.
The best way to get from Buffalo to Chicago Union Station is to fly which takes 3h 36m and costs $100 - $470. Alternatively, you can bus, which costs $80 - $170 and takes 11h 49m, you could also train, which costs $170 - $490 and takes 11h 50m.
What companies run services between Buffalo, NY, USA and Chicago Union Station, IL, USA?
Southwest Airlines and Delta fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW) 5 times a day. Alternatively, you can take a bus from Buffalo to Chicago Union Station via Cleveland Bus Station and Chicago Bus Station in around 11h 49m.
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $75–440
Flights from Rochester to Chicago Midway International Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $80–440
Flights from Rochester to Chicago Midway International Airport via Baltimore
- Ave. Duration
- 4h 10m
- When
- Monday, Thursday, and Friday
- Estimated price
- $110–550
- Website
- united.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 1m
- When
- Every day
- Estimated price
- $65–380
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $95–470
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Chicago Midway International Airport via Detroit
- Ave. Duration
- 3h 44m
- When
- Every day
- Estimated price
- $75–440
Flights from Rochester to Chicago Midway International Airport via Detroit
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $80–440
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- $65–380
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo Depew Station to Chicago Union Station
- Ave. Duration
- 10h 33m
- Frequency
- Twice daily
- Estimated price
- $170–350
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Buffalo to Cleveland Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $30–60
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Chicago Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- Twice daily
- Estimated price
- $50–110
- Website
- https://www.greyhound.com/
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $11–22
- Website
- https://www.greyhound.com/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 15m
- Frequency
- Every 2 hours
- Estimated price
- $28–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $28–40
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $11–20
- Schedules at
- flixbus.com
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More Questions & Answers
Buffalo to Chicago Union Station bus services, operated by Greyhound USA, arrive at Cleveland Bus Station.
Chicago Union Station is 1h behind Buffalo. It is currently 11:45 PM in Buffalo and 10:45 PM in Chicago Union Station.
Buffalo to Chicago Union Station train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Buffalo to Chicago Union Station is 534 miles. It takes approximately 9h 3m to drive from Buffalo to Chicago Union Station.
Book your Buffalo to Chicago Union Station train tickets online with Omio.
Book your Buffalo to Chicago Union Station bus tickets online with Omio and FlixBus.
There are 1295+ hotels available in Chicago Union Station.