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How to get fromBuffalo to Durhamby plane, train, bus (Greyhound, Flixbus), train (Amtrak), car, or bus

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There are 7 ways to get from Buffalo to Durham by plane, train, bus (Greyhound, Flixbus), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Boston Logan Airport, train

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    2. Take the train from Woburn Amtrak Station to Durham Stationtrain train
    5h 57m
    $98–446

  2. Drive  459.3 mi

    cheapest
    1. Drive from Buffalo to Durhamcar car 459.3 mi
    9h 12m
    $84–122

  3. Bus

    1. Take the bus from Buffalo to Bostonbus bus Greyhound US0171
    2. Take the bus from Boston to Portsmouth Bus Stopbus bus FlixBus N2615
    14h 38m
    $99–150

  4. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Bostontrain train Lake Shore Limited
    2. Take the train from Boston to Durham Stationtrain train Downeaster
    15h 9m
    $295–612

  5. Bus to Rochester, fly to Boston Logan Airport, train

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane plane ROC - BOS
    3. Take the train from Woburn Amtrak Station to Durham Stationtrain train
    7h 5m
    $146–647

  6. Fly Buffalo Niagara International Airport to Portland, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Portland (PWM)plane plane BUF - PWM
    2. Take the train from Portland to Durham Stationtrain train
    8h 47m
    $100–445

  7. Bus, train

    1. Take the bus from Buffalo to Ithacabus bus
    2. Take the bus from Ithaca to Bostonbus bus
    3. Take the train from Boston to Durham Stationtrain train
    15h 23m
    $119–187

Buffalo to Durham by bus and train

Calendar7Weekly Services
Duration14h 38mAverage Duration
Ticket$99Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Durham.ExpandLaunch map view
  • Distance: 470.7 mi
  • Duration: 5h 57m

What companies run services between Buffalo, NY, USA and Durham, NH, USA?

You can take a bus from Buffalo to Durham Station via Boston, Portsmouth Bus Stop, Hanover Station, Dover Transportation Center, and Dover in around 14h 38m. Alternatively, you can take a train from Buffalo to Durham Station via Buffalo Depew Station, Boston, Back Bay, North Station, and Boston in around 15h 9m.

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