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How to get fromBuffalo to Gainesvilleby plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound)

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There are 10 ways to get from Buffalo to Gainesville by plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Gainesville Regional Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Gainesville Regional Airport (GNV)plane plane BUF - GNV
    7h 7m
    $94–474

  2. Bus

    1. Take the bus from Buffalo to Newark Penn Stationbus bus
    2. Take the bus from Newark Penn Station to Jacksonvillebus bus
    3. Take the bus from Jacksonville to Gainesvillebus bus
    29h 4m
    $214–343

  3. Train, bus

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Jacksonvilletrain train
    3. Take the bus from Jacksonville to Gainesvillebus bus
    31h 34m
    $752–1,239

  4. Drive  1,097.4 mi

    1. Drive from Buffalo to Gainesvillecar car 1,097.4 mi
    18h 45m
    $201–290

  5. Bus to Rochester, fly to Gainesville Regional Airport

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Gainesville Regional Airport (GNV)plane plane ROC - GNV
    8h 41m
    $152–695

  6. Fly Buffalo Niagara International Airport to Orlando, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Orlando (MCO)plane plane BUF - MCO
    2. Take the bus from Orlando - RedCoach Station, FL to University of Florida - 1956 Gale Lemerand Drbus bus
    7h 55m
    $213–414

  7. Fly Buffalo Niagara International Airport to Jacksonville, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Jacksonville (JAX)plane plane BUF - JAX
    2. Take the bus from Jacksonville to Gainesvillebus bus
    9h 48m
    $113–571

  8. Fly Buffalo Niagara International Airport to Tampa, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Tampa (TPA)plane plane BUF - TPA
    2. Take the bus from Tampa Bus Station to Gainesvillebus bus
    9h 58m
    $184–544

  9. Bus via Atlanta (Greyhound)

    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Gainesville Bus Stopbus bus
    33h 53m
    $238–355

  10. Bus, train

    1. Take the bus from Buffalo, Ny to Pittsburgh, Pabus bus 530
    2. Take the train from Pittsburgh Amtrak Station to Jacksonvilletrain train
    3. Take the bus from Jacksonville to Gainesvillebus bus
    37h
    $612–1,182

Buffalo to Gainesville by bus

Calendar4Weekly Buses
Duration29h 4mAverage Duration
Ticket$214Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Gainesville.ExpandLaunch map view
  • Distance: 955.8 mi
  • Duration: 7h 7m

What companies run services between Buffalo, NY, USA and Gainesville, FL, USA?

Delta and American Airlines fly from Buffalo Niagara International Airport (BUF) to Gainesville Regional Airport (GNV) every 4 hours. Alternatively, you can take a bus from Buffalo to Gainesville via Newark Penn Station and Jacksonville in around 29h 4m.

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Train operators
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