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How to get fromBuffalo to Gainesvilleby plane, bus, train (Amtrak), bus (Greyhound), car, or train

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There are 7 ways to get from Buffalo to Gainesville by plane, bus, train (Amtrak), bus (Greyhound), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Hartsfield-Jackson Atlanta International Airport, bus

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane BUF - ATL
    2. Take the bus from Atlanta to BB Wireless - Gainesvillebus bus
    6h 12m
    $103–453

  2. Train (Amtrak)

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Gainesville Stationtrain train Crescent
    26h 42m
    $402–839

  3. Bus (Greyhound)

    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Gainesvillebus bus
    27h 13m
    $169–317

  4. Drive 812.1 mi

    1. Drive from Buffalo to Gainesvillecar car 812.1 mi
    14h 36m
    $149–215

  5. Fly Buffalo Niagara International Airport to Greenville–Spartanburg International Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Greenville–Spartanburg International Airport (GSP)plane plane BUF - GSP
    2. Take the bus from Taqueria Guadalajara - Greenville to BB Wireless - Gainesvillebus bus
    8h 49m
    $240–985

  6. Bus to Rochester, fly to Hartsfield-Jackson Atlanta International Airport, bus

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane ROC - ATL
    3. Take the bus from Atlanta to BB Wireless - Gainesvillebus bus
    7h 44m
    $207–890

  7. Bus, train

    1. Take the bus from Buffalo to New York Midtownbus bus FlixBus N2686 / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Gainesville Stationtrain train Crescent
    27h
    $336–676

Buffalo to Gainesville by train (Amtrak)

Calendar7Weekly Trains
Duration26h 42mAverage Duration
Ticket$402Cheapest Price
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Questions & Answers

Map of how to get from Buffalo to Gainesville.ExpandLaunch map view
  • Distance: 787.5 mi
  • Duration: 6h 12m

What companies run services between Buffalo, NY, USA and Gainesville, GA, USA?

You can take a train from Buffalo to Gainesville Station via Ny Moynihan Train Hall At Penn Station in around 26h 42m. Alternatively, you can take a bus from Buffalo to Gainesville via Cleveland Bus Station, Atlanta Bus Station, and Gainesville in around 27h 13m.

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