There are 5 ways to get from Buffalo to Great Lakes by plane, bus (Greyhound), train (Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Buffalo Niagara International Airport to Chicago O'Hare International Airport
best- Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)plane BUF - ORD
4h 15m$174–307Drive 530.8 mi
cheapest- Drive from Buffalo to Chicagocar 530.8 mi
9h 2m$91–131Bus (Greyhound)
- Take the bus from Buffalo to Cleveland Bus Stationbus Greyhound US0171 / ...
- Take the bus from Cleveland Bus Station to Chicago Bus Stationbus Greyhound US0164
12h 4m$100–152Train (Amtrak)
- Take the train from Buffalo Depew Station to Chicago Union Stationtrain Lake Shore Limited
12h 5m$294–588Bus to Toronto Pearson International Airport, fly to Windsor Airport, drive
- Take the bus from Buffalo to Mississaugabus
- Fly from Toronto Pearson International Airport (YYZ) to Windsor Airport (YQG)plane YYZ - YQG
- Drive from Windsor-Airport-YQG to Algonac, MIcar
6h 31m$266–875
Buffalo to Great Lakes by bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Buffalo to Great Lakes is to drive which costs $90 - $140 and takes 9h 2m.
The fastest way to get from Buffalo to Great Lakes is to fly which takes 4h 15m and costs $170 - $310.
No, there is no direct bus from Buffalo to Great Lakes. However, there are services departing from Buffalo and arriving at Congress Plaza & Michigan via Cleveland Bus Station and Jefferson & Harrison. The journey, including transfers, takes approximately 12h 4m.
No, there is no direct train from Buffalo to Great Lakes. However, there are services departing from Buffalo and arriving at Washington/Wabash via Buffalo Depew Station and LaSalle/Van Buren. The journey, including transfers, takes approximately 12h 5m.
The distance between Buffalo and Great Lakes is 505 miles. The road distance is 533.9 miles.
The best way to get from Buffalo to Great Lakes without a car is to bus which takes 12h 4m and costs $95 - $160.
It takes approximately 4h 15m to get from Buffalo to Great Lakes, including transfers.
Buffalo to Great Lakes bus services, operated by Greyhound USA, depart from Buffalo station.
Buffalo to Great Lakes train services, operated by Amtrak, depart from Buffalo Depew Station.
The best way to get from Buffalo to Great Lakes is to fly which takes 4h 15m and costs $170 - $310. Alternatively, you can bus, which costs $95 - $160 and takes 12h 4m, you could also train, which costs $290 - $600 and takes 12h 5m.
What companies run services between Buffalo, NY, USA and Great Lakes, MI, USA?
American Airlines and United Airlines fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD) every 4 hours. Alternatively, you can take a bus from Buffalo to Congress Plaza & Michigan via Cleveland Bus Station, Chicago Bus Station, and Jefferson & Harrison in around 12h 4m.
- Website
- united.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 6m
- When
- Every day
- Estimated price
- $40–260
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $60–310
- Website
- aircanada.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 6m
- When
- Every day
- Estimated price
- $40–260
Flights from Toronto Pearson International Airport to Windsor Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- $65–460
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 12m
- When
- Every day
- Estimated price
- $40–260
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Buffalo Depew Station to Chicago Union Station
- Ave. Duration
- 10h 33m
- Frequency
- Twice daily
- Estimated price
- $290–450
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Buffalo to Cleveland Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $35–55
- Website
- Greyhound
Bus from Cleveland Bus Station to Chicago Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- Twice daily
- Estimated price
- $60–95
- Website
- Greyhound
Want to know more about travelling around United States
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Booking & Getting There
Buffalo to Great Lakes bus services, operated by Greyhound USA, arrive at Cleveland Bus Station.
Buffalo to Great Lakes train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Buffalo to Great Lakes is 534 miles. It takes approximately 9h 2m to drive from Buffalo to Great Lakes.
There are 51+ hotels available in Great Lakes.