Rome2Rio

How to get fromBuffalo to Greenevilleby plane, taxi, bus, car, or train

Find Transport to Greeneville

See all options

There are 9 ways to get from Buffalo to Greeneville by plane, taxi, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Tri-Cities Regional Tn/Va Airport, taxi

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Tri-Cities Regional Tn/Va Airport (TRI)plane plane BUF - TRI
    2. Take the taxi from Tri-Cities-Regional-Airport-TRI to Greenevilletaxi taxi
    7h 21m
    $172–542

  2. Fly to Asheville Regional Airport, drive

    cheapest
    1. Fly from Buffalo Niagara International Airport (BUF) to Asheville Regional Airport (AVL)plane plane BUF - AVL
    2. Drive from ART Station to Greenevillecar car
    8h 46m
    $83–428

  3. Bus, drive

    1. Take the bus from Buffalo to Akronbus bus
    2. Take the bus from Akron to Charlestonbus bus
    3. Take the bus from Charleston Bus Station to Winston Salem(Trans Center)bus bus
    4. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    5. Drive from Asheville, NC to Greenevillecar car
    20h 20m
    $110–241

  4. Train, bus, drive

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Greensborotrain train
    3. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    4. Drive from Asheville, NC to Greenevillecar car
    25h 22m
    $265–600

  5. Drive  637.5 mi

    1. Drive from Buffalo to Greenevillecar car 637.5 mi
    11h 1m
    $117–169

  6. Fly to Mcghee Tyson Airport, drive

    1. Fly from Buffalo Niagara International Airport (BUF) to Mcghee Tyson Airport (TYS)plane plane BUF - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Greenevillecar car
    6h 51m
    $177–924

  7. Train, bus, taxi

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the bus from New York, NY to Johnson City, TNbus bus Ny
    3. Take the taxi from Johnson City, TN to Greenevilletaxi taxi
    20h 56m
    $286–463

  8. Bus, taxi

    1. Take the bus from Buffalo to New York Midtownbus bus
    2. Take the bus from New York, NY to Johnson City, TNbus bus Ny
    3. Take the taxi from Johnson City, TN to Greenevilletaxi taxi
    21h 17m
    $248–317

  9. Train, bus, taxi via New York

    1. Take the train from Buffalo to New York Penn Stationtrain train
    2. Take the bus from New York, NY to Johnson City, TNbus bus Ny
    3. Take the taxi from Johnson City, TN to Greenevilletaxi taxi
    21h 38m
    $294–490

Buffalo Niagara International Airport (BUF) to Tri-Cities Regional Tn/Va Airport (TRI) flights

Calendar55Weekly Planes
Duration6h 42mAverage Duration
Ticket$74Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Buffalo to Greeneville.ExpandLaunch map view
  • Distance: 535 mi
  • Duration: 7h 21m

What companies run services between Buffalo, NY, USA and Greeneville, TN, USA?

There is no direct connection from Buffalo to Greeneville. However, you can take the line 24 bus to Genesee Street & 4219 Genesee Street, walk to Buffalo Niagara International Airport (BUF) airport, fly to Tri-Cities Regional Tn/Va Airport (TRI), then take the taxi to Greeneville. Alternatively, you can take a bus from Buffalo to Greeneville via Akron, Charleston, Charleston Bus Station, Winston Salem(Trans Center), and Asheville, NC in around 20h 20m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound