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How to get fromBuffalo to Harrisburg, Paby plane, bus (Greyhound), train (Amtrak), car, train, or bus (Flixbus)

Find Transport to Harrisburg, Pa

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There are 7 ways to get from Buffalo to Harrisburg, Pa by plane, bus (Greyhound), train (Amtrak), car, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Harrisburg International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Harrisburg International Airport (MDT)plane plane BUF - MDT
    5h 43m
    $58–354

  2. Drive  281.6 mi

    cheapest
    1. Drive from Buffalo to Harrisburg, Pacar car 281.6 mi
    5h 33m
    $50–72

  3. Bus via State College

    1. Take the bus from Buffalo to DuBoisbus bus
    2. Take the bus from DuBois to State Collegebus bus
    3. Take the bus from State College Bus Station to Harrisburg Bus Stationbus bus
    9h 40m
    $79–216

  4. Train (Amtrak)

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Harrisburgtrain train Keystone Service / ...
    12h 40m
    $342–541

  5. Fly to Philadelphia International Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Philadelphia International Airport (PHL)plane plane BUF - PHL
    2. Take the train from 30th Street Station to Harrisburgtrain train
    6h 32m
    $119–496

  6. Bus

    1. Take the bus from Buffalo to DuBoisbus bus
    2. Take the bus from DuBois to State Collegebus bus
    3. Take the bus from State College Regional Airport to Harrisburg Bus Stationbus bus
    9h 45m
    $75–229

  7. Bus #2

    1. Take the bus from Buffalo to Scranton Bus Stationbus bus Greyhound US0215 / ...
    2. Take the bus from Scranton, Pa to Harrisburg, Pabus bus 771
    9h 50m
    $76–152

Buffalo to Harrisburg, Pa by bus

Calendar7Weekly Buses
Duration9h 40mAverage Duration
Ticket$79Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Harrisburg, Pa.ExpandLaunch map view
  • Distance: 237.9 mi
  • Duration: 5h 43m

What companies run services between Buffalo, NY, USA and Harrisburg, Pa, PA, USA?

American Airlines, United Airlines, and Delta fly from Buffalo Niagara International Airport (BUF) to Harrisburg International Airport (MDT) every 2 hours. Alternatively, you can take a bus from Buffalo to Harrisburg Bus Station via DuBois, State College, and State College Bus Station in around 9h 40m.

Airlines
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