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How to get fromBuffalo to Hyannis Portby plane, bus (Greyhound), train, bus, car, or bus (Flixbus)

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There are 8 ways to get from Buffalo to Hyannis Port by plane, bus (Greyhound), train, bus, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Barnstable Municipal Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Barnstable Municipal Airport (HYA)plane plane BUF - HYA
    6h 41m
    $107–634

  2. Bus

    cheapest
    1. Take the bus from Buffalo to Bostonbus bus Greyhound US0171
    2. Take the bus from Boston South Station to Hyannis Transportation Centerbus bus Boston
    13h 46m
    $92–182

  3. Train, bus

    1. Take the train from Buffalo Depew Station to Bostontrain train Lake Shore Limited
    2. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus Hyannis - South Shore to Logan Airport
    16h 22m
    $192–503

  4. Drive 513.5 mi

    1. Drive from Buffalo to Hyannis Portcar car 513.5 mi
    9h 4m
    $94–136

  5. Fly Buffalo Niagara International Airport to Boston Logan Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    2. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    6h 29m
    $107–491

  6. Bus to Rochester, fly to Boston Logan Airport, bus

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane plane ROC - BOS
    3. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    8h 1m
    $121–458

  7. Fly Buffalo Niagara International Airport to Provincetown Municipal Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Provincetown Municipal Airport (PVC)plane plane BUF - PVC
    2. Take the bus from Provincetown to Hyannis Transportation Centerbus bus
    9h 34m
    $107–611

  8. Bus via Ithaca

    1. Take the bus from Buffalo to Ithacabus bus
    2. Take the bus from Ithaca to Bostonbus bus
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    16h 18m
    $111–180

Buffalo to Hyannis Port by bus

Calendar7Weekly Buses
Duration13h 46mAverage Duration
Ticket$92Cheapest Price
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Questions & Answers

Map of how to get from Buffalo to Hyannis Port.ExpandLaunch map view
  • Distance: 453.8 mi
  • Duration: 6h 41m

What companies run services between Buffalo, NY, USA and Hyannis Port, MA, USA?

JetBlue Airways, Cape Air, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Barnstable Municipal Airport (HYA) every 4 hours. Alternatively, you can take a bus from Buffalo to Resort and Conference Center at Hyannis via Boston, Boston South Station, and Hyannis Transportation Center in around 13h 46m.

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