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How to get fromBuffalo to Jacksonvilleby plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or train

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There are 9 ways to get from Buffalo to Jacksonville by plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Jacksonville

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Jacksonville (JAX)plane plane BUF - JAX
    7h 19m
    $103–555

  2. Bus

    1. Take the bus from Buffalo to Newark Penn Stationbus bus FlixBus N2686 / ...
    2. Take the bus from Newark Penn Station to Jacksonvillebus bus FlixBus N2473
    26h 35m
    $204–327

  3. Train (Amtrak)

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Jacksonvilletrain train Silver Meteor
    28h 59m
    $742–1,223

  4. Drive  1,033.8 mi

    1. Drive from Buffalo to Jacksonvillecar car 1,033.8 mi
    17h 28m
    $189–273

  5. Bus to Rochester, fly to Jacksonville

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Jacksonville (JAX)plane plane ROC - JAX
    8h 23m
    $161–746

  6. Fly Buffalo Niagara International Airport to Brunswick Golden Isles Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Brunswick Golden Isles Airport (BQK)plane plane BUF - BQK
    2. Take the bus from Brunswick to Jacksonvillebus bus
    8h 14m
    $117–507

  7. Bus to Toronto Pearson International Airport, fly to Jacksonville

    1. Take the bus from Buffalo to Mississaugabus bus
    2. Fly from Toronto Pearson International Airport (YYZ) to Jacksonville (JAX)plane plane YYZ - JAX
    9h 27m
    $112–512

  8. Fly Buffalo Niagara International Airport to Gainesville Regional Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Gainesville Regional Airport (GNV)plane plane BUF - GNV
    2. Take the bus from Gainesville to Jacksonvillebus bus
    9h 37m
    $104–490

  9. Bus, train

    1. Take the bus from Buffalo, Ny to Pittsburgh, Pabus bus 530
    2. Take the train from Pittsburgh Amtrak Station to Jacksonvilletrain train Floridian
    34h 25m
    $602–1,166

Buffalo to Jacksonville by bus

Calendar4Weekly Buses
Duration26h 35mAverage Duration
Ticket$204Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Jacksonville.ExpandLaunch map view
  • Distance: 905.1 mi
  • Duration: 7h 19m

What companies run services between Buffalo, NY, USA and Jacksonville, FL, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Jacksonville (JAX) every 2 hours. Alternatively, you can take a bus from Buffalo to Jacksonville via Newark Penn Station in around 26h 35m.

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