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How to get fromBuffalo to Jeffersonvilleby plane, car, bus, bus (Greyhound), or train

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There are 7 ways to get from Buffalo to Jeffersonville by plane, car, bus, bus (Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Blue Grass Airport, drive

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Blue Grass Airport (LEX)plane plane BUF - LEX
    2. Drive from Lexington-Airport-LEX to Jeffersonvillecar car
    6h 14m
    $195–1,047

  2. Bus

    cheapest
    1. Take the bus from Buffalo, NY to Cincinnati, OHbus bus Buffalo
    2. Take the bus from Cincinnati Bus Station to Louisville Bus Stationbus bus Greyhound US0135 / ...
    14h 1m
    $64–189

  3. Bus via Akron

    1. Take the bus from Buffalo to Akronbus bus Bsb 11
    2. Take the bus from Akron to Louisvillebus bus Bsb 27
    13h 29m
    $146–208

  4. Drive 531.1 mi

    1. Drive from Buffalo to Jeffersonvillecar car 531.1 mi
    9h 2m
    $97–140

  5. Fly Buffalo Niagara International Airport to Louisville International Airport

    1. Fly from Buffalo Niagara International Airport (BUF) to Louisville International Airport (SDF)plane plane BUF - SDF
    7h 23m
    $124–734

  6. Bus to Rochester, fly to Louisville International Airport

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Louisville International Airport (SDF)plane plane ROC - SDF
    8h 26m
    $402–651

  7. Train, bus

    1. Take the train from Buffalo Depew Station to Toledotrain train Lake Shore Limited
    2. Take the bus from Toledo Bus Stop to Louisville Bus Stationbus bus Greyhound US0135 / ...
    14h 42m
    $169–451

Buffalo to Jeffersonville by bus and foot

Calendar7Weekly Services
Duration13h 29mAverage Duration
Ticket$146Cheapest Price
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Questions & Answers

Map of how to get from Buffalo to Jeffersonville.ExpandLaunch map view
  • Distance: 539.7 mi
  • Duration: 6h 14m

What companies run services between Buffalo, NY, USA and Jeffersonville, IN, USA?

You can take a bus from Buffalo to Court @ Meigs via Akron, Louisville, Chestnut @ 13th, Chestnut @ 8th, and Liberty @ Roy Wilkins in around 13h 29m. Alternatively, Southwest Airlines, United Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Louisville International Airport (SDF) every 2 hours.

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