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How to get fromBuffalo to Knoxville Airport (TYS)by plane, car, bus (Greyhound), bus, shuttle, train, or bus (Flixbus)

Find Transport to Knoxville Airport (TYS)

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There are 10 ways to get from Buffalo to Knoxville Airport (TYS) by plane, car, bus (Greyhound), bus, shuttle, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Mcghee Tyson Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Mcghee Tyson Airport (TYS)plane plane BUF - TYS
    4h 59m
    $176–978

  2. Drive 694.8 mi

    cheapest
    1. Drive from Buffalo to Knoxville Airport (TYS)car car 694.8 mi
    11h 46m
    $127–184

  3. Fly Buffalo Niagara International Airport to Nashville, drive

    1. Fly from Buffalo Niagara International Airport (BUF) to Nashville (BNA)plane plane BUF - BNA
    2. Drive from Nashville-Airport-BNA to Knoxville-Airport-TYScar car
    5h 56m
    $136–628

  4. Bus via Knoxville

    1. Take the bus from Buffalo to Port Authority Bus Terminalbus bus Greyhound US0205 / ...
    2. Take the bus from New York to Knoxvillebus bus Nyc
    21h 44m
    $245–501

  5. Bus to Rochester, fly to Mcghee Tyson Airport

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Mcghee Tyson Airport (TYS)plane plane ROC - TYS
    6h 29m
    $199–994

  6. Shuttle to Toronto Pearson International Airport, fly to Mcghee Tyson Airport

    1. Take a shuttle bus from Buffalo Airport to Pearson International Airport Terminal 1shuttle bus
    2. Fly from Toronto Pearson International Airport (YYZ) to Mcghee Tyson Airport (TYS)plane plane YYZ - TYS
    8h 46m
    $206–748

  7. Shuttle to Toronto Island Airport, fly to Mcghee Tyson Airport

    1. Take a shuttle bus from Buffalo Airport to Pearson International Airport Terminal 1shuttle bus
    2. Fly from Toronto Island Airport (YTZ) to Mcghee Tyson Airport (TYS)plane plane YTZ - TYS
    10h 17m
    $232–857

  8. Train, bus

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    22h 3m
    $303–481

  9. Train, bus via New York

    1. Take the train from Buffalo to New York Penn Stationtrain train VIA Rail
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    22h 45m
    $283–479

  10. Bus

    1. Take the bus from Buffalo to New York Midtownbus bus FlixBus N2686 / ...
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    23h 19m
    $235–312

Buffalo Niagara International Airport (BUF) to Mcghee Tyson Airport (TYS) flights

Calendar90Weekly Planes
Duration4h 50mAverage Duration
Ticket$178Cheapest Price
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Questions & Answers

Map of how to get from Buffalo to Knoxville Airport (TYS).ExpandLaunch map view
  • Distance: 577.2 mi
  • Duration: 4h 59m

What companies run services between Buffalo, NY, USA and Knoxville Airport (TYS), USA?

Delta, United Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Mcghee Tyson Airport (TYS) hourly. Alternatively, you can take a bus from Buffalo to Knoxville Airport (TYS) via Port Authority Bus Terminal, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 21h 44m.

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