Rome2Rio

How to get fromBuffalo to Lexington-Fayetteby plane, bus, car, or train

Find Transport to Lexington-Fayette

See all options

There are 10 ways to get from Buffalo to Lexington-Fayette by plane, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Blue Grass Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Blue Grass Airport (LEX)plane plane BUF - LEX
    6h 29m
    $68–403

  2. Bus, drive #2

    cheapest
    1. Take the bus from Buffalo, NY to Robert K Pfaff Transit Center - Akronbus bus
    2. Take the bus from Robert K Pfaff Transit Center - Akron to Louisville, KY Bus Stationbus bus
    3. Drive from Middletown Station @ Target to Lexington-Fayettecar car
    15h 29m
    $65–165

  3. Bus, drive

    1. Take the bus from Buffalo to Akronbus bus
    2. Take the bus from Akron to Louisvillebus bus
    3. Drive from Middletown Station @ Target to Lexington-Fayettecar car
    15h 29m
    $70–170

  4. Drive  514.9 mi

    1. Drive from Buffalo to Lexington-Fayettecar car 514.9 mi
    8h 44m
    $94–136

  5. Fly Buffalo Niagara International Airport to Covington, drive

    1. Fly from Buffalo Niagara International Airport (BUF) to Covington (CVG)plane plane BUF - CVG
    2. Drive from Covington (CVG) to Lexington-Fayettecar car
    6h 14m
    $166–263

  6. Fly Buffalo Niagara International Airport to Louisville International Airport, drive

    1. Fly from Buffalo Niagara International Airport (BUF) to Louisville International Airport (SDF)plane plane BUF - SDF
    2. Drive from Louisville-Airport-SDF to Lexington-Fayettecar car
    6h 25m
    $126–673

  7. Bus to Rochester, fly to Blue Grass Airport

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Blue Grass Airport (LEX)plane plane ROC - LEX
    7h 47m
    $121–593

  8. Bus to Toronto Pearson International Airport, fly to Covington, drive

    1. Take the bus from Buffalo to Mississaugabus bus
    2. Fly from Toronto Pearson International Airport (YYZ) to Covington (CVG)plane plane YYZ - CVG
    3. Drive from Covington (CVG) to Lexington-Fayettecar car
    8h 3m
    $640–1,080

  9. Bus, drive #3

    1. Take the bus from Buffalo, NY to Cincinnati, OHbus bus
    2. Take the bus from Greyhound Station Cincinnati to Louisville, KY Bus Stationbus bus
    3. Drive from Middletown Station @ Target to Lexington-Fayettecar car
    16h 14m
    $75–147

  10. Train, bus, drive

    1. Take the train from Buffalo Depew Station to Toledotrain train
    2. Take the bus from Toledo Bus Stop to Louisville Bus Stationbus bus
    3. Drive from Middletown Station @ Target to Lexington-Fayettecar car
    17h 10m
    $135–402

Buffalo Niagara International Airport (BUF) to Blue Grass Airport (LEX) flights

Calendar120Weekly Planes
Duration5h 35mAverage Duration
Ticket$69Cheapest Price
See schedules

Questions & Answers

Map of how to get from Buffalo to Lexington-Fayette.ExpandLaunch map view
  • Distance: 477 mi
  • Duration: 6h 29m

What companies run services between Buffalo, NY, USA and Lexington-Fayette, KY, USA?

Delta, American Airlines, and United Airlines fly from Buffalo Niagara International Airport (BUF) to Blue Grass Airport (LEX) hourly.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound