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How to get fromBuffalo to Littletonby plane, taxi, bus (Greyhound), train (Amtrak), car, train, or bus

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There are 7 ways to get from Buffalo to Littleton by plane, taxi, bus (Greyhound), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Manchester Airport, taxi

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Manchester Airport (MHT)plane plane BUF - MHT
    2. Take the taxi from Manchester-Airport-MHT to Littletontaxi taxi
    5h 53m
    $316–798

  2. Drive 422.8 mi

    cheapest
    1. Drive from Buffalo to Littletoncar car 422.8 mi
    8h 29m
    $78–112

  3. Bus (Greyhound)

    1. Take the bus from Buffalo to Bostonbus bus Greyhound US0171
    2. Take the bus from Boston to Ayer MAbus bus Greyhound US0256S
    12h 37m
    $95–170

  4. Train

    1. Take the train from Buffalo Depew Station to Bostontrain train Lake Shore Limited
    2. Take the train from Porter to Littleton/Route 495train train Fitchburg Line
    14h 38m
    $169–491

  5. Fly Buffalo Niagara International Airport to Boston Logan Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    2. Take the train from North Station to Littleton/Route 495train train
    5h
    $93–474

  6. Bus to Rochester, fly to Boston Logan Airport, train

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane plane ROC - BOS
    3. Take the train from North Station to Littleton/Route 495train train
    6h 33m
    $112–471

  7. Bus, train

    1. Take the bus from Buffalo to Ithacabus bus
    2. Take the bus from Ithaca to Bostonbus bus
    3. Take the train from Porter to Littleton/Route 495train train
    14h 34m
    $104–179

Buffalo Niagara International Airport (BUF) to Manchester Airport (MHT) flights

Calendar86Weekly Planes
Duration5h 22mAverage Duration
Ticket$92Cheapest Price
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Questions & Answers

Map of how to get from Buffalo to Littleton.ExpandLaunch map view
  • Distance: 415.3 mi
  • Duration: 5h 53m

What companies run services between Buffalo, NY, USA and Littleton, MA, USA?

You can take a bus from Buffalo to Littleton via Boston and Ayer MA in around 12h 37m. Alternatively, you can take a train from Buffalo to Littleton via Buffalo Depew Station, Boston, South Station, Porter, Porter, and Littleton/Route 495 in around 14h 38m.

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