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How to get fromBuffalo to Louisvilleby plane, bus, or car

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There are 6 ways to get from Buffalo to Louisville by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Louisville International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Louisville International Airport (SDF)plane plane BUF - SDF
    6h 16m
    $113–655

  2. Bus #2

    cheapest
    1. Take the bus from Buffalo, NY to Robert K Pfaff Transit Center - Akronbus bus Buffalo
    2. Take the bus from Robert K Pfaff Transit Center - Akron to Louisville, KY Bus Stationbus bus Cleveland
    12h
    $52–141

  3. Bus

    1. Take the bus from Buffalo to Akronbus bus Bsb 11
    2. Take the bus from Akron to Louisvillebus bus Bsb 27
    12h
    $57–146

  4. Drive  530.9 mi

    1. Drive from Buffalo to Louisvillecar car 530.9 mi
    9h 1m
    $97–140

  5. Fly Buffalo Niagara International Airport to Blue Grass Airport, drive

    1. Fly from Buffalo Niagara International Airport (BUF) to Blue Grass Airport (LEX)plane plane BUF - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    6h 20m
    $85–421

  6. Bus to Rochester, fly to Louisville International Airport

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Louisville International Airport (SDF)plane plane ROC - SDF
    7h 35m
    $150–796

Buffalo to Louisville by bus

Calendar7Weekly Buses
Duration12hAverage Duration
Ticket$57Cheapest Price
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Questions & Answers

Map of how to get from Buffalo to Louisville.ExpandLaunch map view
  • Distance: 511.1 mi
  • Duration: 6h 16m

What companies run services between Buffalo, NY, USA and Louisville, KY, USA?

Delta, Southwest Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Louisville International Airport (SDF) hourly. Alternatively, you can take a bus from Buffalo to Louisville via Akron in around 12h.

Airlines
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