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How to get fromBuffalo to Louisville, KYby plane, car, bus, or bus (Flixbus, Greyhound)

Find Transport to Louisville, KY

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There are 7 ways to get from Buffalo to Louisville, KY by plane, car, bus, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Blue Grass Airport, drive

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Blue Grass Airport (LEX)plane plane BUF - LEX
    2. Drive from Lexington-Airport-LEX to Louisville, KYcar car
    6h 9m
    $83–436

  2. Bus

    cheapest
    1. Take the bus from Buffalo to Akronbus bus Bsb 11
    2. Take the bus from Akron to Louisvillebus bus Bsb 27
    12h
    $57–146

  3. Drive  532.2 mi

    1. Drive from Buffalo to Louisville, KYcar car 532.2 mi
    9h 2m
    $91–132

  4. Fly Buffalo Niagara International Airport to Louisville International Airport

    1. Fly from Buffalo Niagara International Airport (BUF) to Louisville International Airport (SDF)plane plane BUF - SDF
    6h 42m
    $127–781

  5. Bus to Rochester, fly to Louisville International Airport

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Louisville International Airport (SDF)plane plane ROC - SDF
    8h 12m
    $211–1,147

  6. Bus to Toronto Pearson International Airport, fly to Louisville International Airport

    1. Take the bus from Buffalo to Torontobus bus
    2. Fly from Toronto Pearson International Airport (YYZ) to Louisville International Airport (SDF)plane plane YYZ - SDF
    8h 40m
    $117–680

  7. Bus via Columbus

    1. Take the bus from Buffalo to Columbusbus bus FlixBus 2526
    2. Take the bus from Columbus to Louisville Bus Stationbus bus Greyhound US0105
    14h 28m
    $78–146

Buffalo to Louisville, KY by bus

Calendar7Weekly Buses
Duration12hAverage Duration
Ticket$57Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Louisville, KY.ExpandLaunch map view
  • Distance: 540.8 mi
  • Duration: 6h 9m

What companies run services between Buffalo, NY, USA and Louisville, KY, USA?

You can take a bus from Buffalo to Louisville via Akron in around 12h. Alternatively, Delta, United Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Louisville International Airport (SDF) every 2 hours.

Airlines
Bus operators

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