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How to get fromBuffalo to Medfordby plane, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)

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There are 6 ways to get from Buffalo to Medford by plane, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    3h 26m
    $88–460

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Buffalo to Bostonbus bus Greyhound US0171
    11h 38m
    $72–140

  3. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Bostontrain train Lake Shore Limited
    12h 55m
    $155–468

  4. Drive 454.8 mi

    1. Drive from Buffalo to Medfordcar car 454.8 mi
    8h
    $83–120

  5. Bus to Rochester, fly

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane plane ROC - BOS
    4h 58m
    $106–457

  6. Bus via Ithaca (Flixbus)

    1. Take the bus from Buffalo to Ithacabus bus FlixBus 2685 / ...
    2. Take the bus from Ithaca to Bostonbus bus FlixBus 2691
    13h 3m
    $90–157

Buffalo to Medford by bus and foot (Greyhound)

Calendar7Weekly Services
Duration11h 38mAverage Duration
Ticket$72Cheapest Price
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Questions & Answers

Map of how to get from Buffalo to Medford.ExpandLaunch map view
  • Distance: 419.8 mi
  • Duration: 3h 26m

What companies run services between Buffalo, NY, USA and Medford, MA, USA?

American Airlines, JetBlue Airways, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS) every 4 hours. Alternatively, Greyhound USA operates a bus from Buffalo to Boston once daily. Tickets cost $70–140 and the journey takes 10h 5m.

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Need to know: Greyhound

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