There are 6 ways to get from Buffalo to Mesa by plane, train, bus, bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Buffalo Niagara International Airport
best- Fly from Buffalo Niagara International Airport (BUF) to Phoenix (PHX)plane BUF - PHX
6h 42m$188–830Train, bus via Flagstaff
- Take the train from Buffalo Depew Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Flagstafftrain
- Take the bus from Flagstaff Train Station to Tempebus
2d$686–1,618Bus
- Take the bus from Buffalo, NY to Columbus - Mound Stbus
- Take the bus from Columbus to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Phoenix Bus Stationbus
2d 3h$319–645Drive 2,175.5 mi
- Drive from Buffalo to Mesacar 2,175.5 mi
35h 36m$397–574Bus to Rochester, fly
- Take the bus from Buffalo to Rochester Bus Stopbus
- Fly from Rochester (ROC) to Phoenix (PHX)plane ROC - PHX
9h 47m$221–896Train, bus
- Take the train from Buffalo Depew Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Tucson Amtrak Stationtrain
- Take the bus from Tucson Downtown to Tempebus
2d 23h$830–2,004
Buffalo to Mesa by train, bus, and tram
Questions & Answers
The cheapest way to get from Buffalo to Mesa is to bus which costs $310 - $650 and takes 2 days 3h.
The fastest way to get from Buffalo to Mesa is to fly which takes 6h 42m and costs $180 - $850.
No, there is no direct bus from Buffalo to Mesa. However, there are services departing from Buffalo, NY and arriving at University Dr & Mesa Dr via Columbus, St Louis Bus Station, Phoenix Bus Station, Phoenix Sky Harbor Airport/44th Street Sky Train Station and University Dr & Rural Rd. The journey, including transfers, takes approximately 2 days 3h.
The distance between Buffalo and Mesa is 1942 miles. The road distance is 2188.2 miles.
The best way to get from Buffalo to Mesa without a car is to train and bus via Flagstaff which takes 2 days 0h and costs $650 - $1,700.
It takes approximately 6h 42m to get from Buffalo to Mesa, including transfers.
Buffalo to Mesa bus services, operated by Barons Bus, depart from Buffalo, NY station.
The best way to get from Buffalo to Mesa is to fly which takes 6h 42m and costs $180 - $850. Alternatively, you can bus, which costs $310 - $650 and takes 2 days 3h.
Buffalo to Mesa bus services, operated by Barons Bus, arrive at Columbus - Mound St station.
Mesa is 3h behind Buffalo. It is currently 8:24 AM in Buffalo and 5:24 AM in Mesa.
What companies run services between Buffalo, NY, USA and Mesa, AZ, USA?
Southwest Airlines, United Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Phoenix (PHX) every 4 hours. Alternatively, you can take a bus from Buffalo, NY to University Dr & Mesa Dr via Columbus, St Louis Bus Station, Phoenix Bus Station, Phoenix Sky Harbor Airport/44th Street Sky Train Station, Tempe, and University Dr & Rural Rd in around 2d 3h.
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Phoenix
- Ave. Duration
- 4h 35m
- When
- Saturday
- Estimated price
- $180–800
Flights from Buffalo Niagara International Airport to Phoenix via Chicago Midway
- Ave. Duration
- 6h 29m
- When
- Tuesday to Friday
- Estimated price
- $180–800
Flights from Buffalo Niagara International Airport to Phoenix via Denver
- Ave. Duration
- 6h 26m
- When
- Saturday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $180–800
Flights from Buffalo Niagara International Airport to Phoenix via Nashville
- Ave. Duration
- 6h 20m
- When
- Saturday
- Estimated price
- $190–850
Flights from Rochester to Phoenix via Chicago Midway
- Ave. Duration
- 6h 20m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $190–850
Flights from Rochester to Phoenix via Baltimore
- Ave. Duration
- 8h 17m
- When
- Every day
- Estimated price
- $220–900
- Website
- united.com
Flights from Buffalo Niagara International Airport to Phoenix via Denver
- Ave. Duration
- 6h 33m
- When
- Every day
- Estimated price
- $180–800
Flights from Buffalo Niagara International Airport to Phoenix via Chicago O'Hare
- Ave. Duration
- 7h 7m
- When
- Every day
- Estimated price
- $180–800
Flights from Rochester to Phoenix via Chicago O'Hare
- Ave. Duration
- 7h 51m
- When
- Every day
- Estimated price
- $190–850
Flights from Rochester to Phoenix via Washington Dulles
- Ave. Duration
- 7h 54m
- When
- Monday to Friday
- Estimated price
- $220–900
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Phoenix via Detroit
- Ave. Duration
- 6h 34m
- When
- Every day
- Estimated price
- $180–800
Flights from Rochester to Phoenix via Detroit
- Ave. Duration
- 7h 31m
- When
- Every day
- Estimated price
- $190–850
Flights from Rochester to Phoenix via Atlanta
- Ave. Duration
- 8h 15m
- When
- Every day
- Estimated price
- $220–950
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Phoenix via Chicago O'Hare
- Ave. Duration
- 6h 43m
- When
- Every day
- Estimated price
- $180–800
Flights from Rochester to Phoenix via Chicago O'Hare
- Ave. Duration
- 7h 29m
- When
- Every day
- Estimated price
- $190–850
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Buffalo Depew Station to Chicago Union Station
- Ave. Duration
- 10h 33m
- Frequency
- Twice daily
- Estimated price
- $160–340
- Website
- Amtrak
Train from Chicago Union Station to Flagstaff
- Ave. Duration
- 31h 44m
- Frequency
- Once daily
- Estimated price
- $500–1,100
- Website
- Amtrak
Train from Buffalo Depew Station to Chicago Union Station
- Ave. Duration
- 10h 33m
- Frequency
- Twice daily
- Estimated price
- $160–340
- Website
- Amtrak
Train from Chicago Union Station to Tucson Amtrak Station
- Ave. Duration
- 2d 6h
- Frequency
- 3 times a week
- Estimated price
- $650–1,500
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Flagstaff Train Station to Tempe
- Ave. Duration
- 2h 50m
- Frequency
- 5 times a week
- Estimated price
- $22–40
- Schedules at
- Flixbus USA
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $11–18
- Schedules at
- Flixbus USA
Bus from Tucson Downtown to Tempe
- Ave. Duration
- 1h 50m
- Frequency
- 5 times a day
- Estimated price
- $16–26
- Schedules at
- Flixbus USA
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Buffalo, NY to Columbus - Mound St
- Ave. Duration
- 7h 5m
- Frequency
- Once daily
- Estimated price
- $35–80
- Website
- Barons Bus
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Columbus to St Louis Bus Station
- Ave. Duration
- 9h 5m
- Frequency
- 3 times a day
- Estimated price
- $60–120
- Website
- Greyhound
Bus from St Louis Bus Station to Phoenix Bus Station
- Ave. Duration
- 30h
- Frequency
- Twice daily
- Estimated price
- $220–440
- Website
- Greyhound
Bus from Buffalo to Rochester Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $11–22
- Website
- Greyhound
Want to know more about travelling around United States
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More Questions & Answers
Yes, the driving distance between Buffalo to Mesa is 2188 miles. It takes approximately 35h 36m to drive from Buffalo to Mesa.
Book your Buffalo to Mesa bus tickets online with Omio.
There are 2185+ hotels available in Mesa.












