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How to get fromBuffalo to Mesaby plane, train, bus, bus (Greyhound), or car

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There are 7 ways to get from Buffalo to Mesa by plane, train, bus, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Phoenix (PHX)plane plane BUF - PHX
    7h 8m
    $144–654

  2. Train, bus via Flagstaff

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Flagstafftrain train
    3. Take the bus from Flagstaff Train Station to Phoenix Sky Harbor Airport/44th Street Sky Train Stationbus bus
    2d
    $556–1,469

  3. Bus

    1. Take the bus from Buffalo to Columbusbus bus
    2. Take the bus from Columbus to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Phoenix Bus Stationbus bus
    2d 3h
    $344–575

  4. Drive  2,175.5 mi

    1. Drive from Buffalo to Mesacar car 2,175.5 mi
    35h 36m
    $397–574

  5. Bus to Rochester, fly

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Phoenix (PHX)plane plane ROC - PHX
    10h 24m
    $231–943

  6. Bus to Toronto Pearson International Airport, fly

    1. Take the bus from Buffalo to Mississaugabus bus
    2. Fly from Toronto Pearson International Airport (YYZ) to Phoenix (PHX)plane plane YYZ - PHX
    10h 36m
    $257–761

  7. Train, bus

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Tucson Amtrak Stationtrain train
    3. Take the bus from Tucson Downtown to Tempebus bus
    3d
    $642–1,631

Buffalo to Mesa by train, bus, and tram

Calendar7Weekly Services
Duration2dAverage Duration
Ticket$556Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Mesa.ExpandLaunch map view
  • Distance: 1,932.4 mi
  • Duration: 7h 8m

What companies run services between Buffalo, NY, USA and Mesa, AZ, USA?

Southwest Airlines, Delta, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Phoenix (PHX) every 4 hours. Alternatively, you can take a bus from Buffalo to University Dr & Mesa Dr via Columbus, St Louis Bus Station, Phoenix Bus Station, Phoenix Sky Harbor Airport/44th Street Sky Train Station, Tempe, and University Dr & Rural Rd in around 2d 3h.

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Need to know: Greyhound

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