There are 3 ways to get from Buffalo to Mesa by plane, train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Buffalo Niagara International Airport (BUF) to Phoenix (PHX)plane BUF - PHX
7h 8m$144–654Train, bus
- Take the train from Buffalo Depew Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Flagstafftrain
- Take the bus from Flagstaff Train Station to Phoenix Sky Harbor Airport/44th Street Sky Train Stationbus
2d$1,217–2,121Drive 2,175.5 mi
- Drive from Buffalo to Mesacar 2,175.5 mi
35h 36m$397–574
Buffalo to Mesa by train, bus, and tram
Comparing Your Travel Options
The cheapest way to get from Buffalo to Mesa is to fly which costs $140 - $700 and takes 7h 8m.
The fastest way to get from Buffalo to Mesa is to fly which takes 7h 8m and costs $140 - $700.
The distance between Buffalo and Mesa is 1944 miles. The road distance is 2188.2 miles.
The best way to get from Buffalo to Mesa without a car is to train and bus which takes 2 days 0h and costs $1,200 - $2,200.
It takes approximately 7h 8m to get from Buffalo to Mesa, including transfers.
Mesa is 3h behind Buffalo. It is currently 8:54 AM in Buffalo and 5:54 AM in Mesa.
Yes, the driving distance between Buffalo to Mesa is 2188 miles. It takes approximately 35h 36m to drive from Buffalo to Mesa.
There are 2657+ hotels available in Mesa.
What companies run services between Buffalo, NY, USA and Mesa, AZ, USA?
Southwest Airlines, Delta, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Phoenix (PHX) every 4 hours.
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Phoenix
- Ave. Duration
- 4h 46m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $140–650
Flights from Buffalo Niagara International Airport to Phoenix via Chicago Midway
- Ave. Duration
- 6h 39m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $140–650
Flights from Buffalo Niagara International Airport to Phoenix via Denver
- Ave. Duration
- 6h 30m
- When
- Tuesday and Wednesday
- Estimated price
- $150–650
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Phoenix via Detroit
- Ave. Duration
- 6h 37m
- When
- Every day
- Estimated price
- $140–650
Flights from Buffalo Niagara International Airport to Phoenix via Minneapolis
- Ave. Duration
- 6h 53m
- When
- Friday and Saturday
- Estimated price
- $150–650
- Website
- united.com
Flights from Buffalo Niagara International Airport to Phoenix via Denver
- Ave. Duration
- 6h 47m
- When
- Every day
- Estimated price
- $150–650
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Phoenix via Chicago O'Hare
- Ave. Duration
- 6h 57m
- When
- Every day
- Estimated price
- $140–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Buffalo Depew Station to Chicago Union Station
- Ave. Duration
- 10h 33m
- Frequency
- Twice daily
- Estimated price
- $290–450
- Website
- Amtrak
Train from Chicago Union Station to Flagstaff
- Ave. Duration
- 31h 44m
- Frequency
- Once daily
- Estimated price
- $900–1,500
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Flagstaff Train Station to Phoenix Sky Harbor Airport/44th Street Sky Train Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $23–35
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide






