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How to get fromBuffalo to Mobileby plane, bus (Greyhound), train (Amtrak), car, or bus

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There are 8 ways to get from Buffalo to Mobile by plane, bus (Greyhound), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Mobile Regional Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Mobile Regional Airport (MOB)plane plane BUF - MOB
    6h 21m
    $127–532

  2. Fly Buffalo Niagara International Airport to Destin–Fort Walton Beach Airport, drive

    cheapest
    1. Fly from Buffalo Niagara International Airport (BUF) to Destin–Fort Walton Beach Airport (VPS)plane plane BUF - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Mobilecar car
    8h 8m
    $116–510

  3. Bus (Greyhound)

    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Toledo Bus Stopbus bus
    3. Take the bus from Toledo Bus Stop to Montgomery Intermodal Centerbus bus
    4. Take the bus from Montgomery Intermodal Center to Mobile Bus Stationbus bus
    30h 6m
    $224–345

  4. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train
    36h 15m
    $822–1,504

  5. Drive  1,126.8 mi

    1. Drive from Buffalo to Mobilecar car 1,126.8 mi
    19h 57m
    $206–297

  6. Bus to Rochester, fly to Mobile Regional Airport

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Mobile Regional Airport (MOB)plane plane ROC - MOB
    7h 30m
    $190–733

  7. Fly Buffalo Niagara International Airport to Gulfport-Biloxi Regional Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Gulfport-Biloxi Regional Airport (GPT)plane plane BUF - GPT
    2. Take the bus from Gulfport to Mobilebus bus
    8h 19m
    $164–583

  8. Bus via Atlanta

    1. Take the bus from Buffalo to Mansfieldbus bus
    2. Take the bus from Mansfield Bus Stop to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Mobile Bus Stationbus bus
    33h 49m
    $204–351

Buffalo to Mobile by bus (Greyhound)

Calendar7Weekly Buses
Duration30h 6mAverage Duration
Ticket$224Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Mobile.ExpandLaunch map view
  • Distance: 1,021 mi
  • Duration: 6h 21m

What companies run services between Buffalo, NY, USA and Mobile, AL, USA?

Delta, American Airlines, and United Airlines fly from Buffalo Niagara International Airport (BUF) to Mobile Regional Airport (MOB) every 4 hours. Alternatively, you can take a bus from Buffalo to Govt EB Mid Block Past Joachim St via Cleveland Bus Station, Toledo Bus Stop, Montgomery Intermodal Center, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 30h 6m.

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