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How to get fromBuffalo to Myrtle Beachby plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound)

Find Transport to Myrtle Beach

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There are 6 ways to get from Buffalo to Myrtle Beach by plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR)plane plane BUF - MYR
    5h 22m
    $78–396

  2. Bus

    1. Take the bus from Buffalo to Newark Penn Stationbus bus
    2. Take the bus from Newark Penn Station to Fayetteville Bus Stationbus bus
    3. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    23h 15m
    $176–282

  3. Train, bus

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Fayetteville Amtrak Stationtrain train
    3. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    24h 24m
    $568–885

  4. Drive  760.8 mi

    1. Drive from Buffalo to Myrtle Beachcar car 760.8 mi
    15h 35m
    $139–201

  5. Bus to Rochester, fly

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Myrtle Beach (MYR)plane plane ROC - MYR
    4h 52m
    $126–547

  6. Bus via Raleigh

    1. Take the bus from Buffalo to Port Authority Bus Terminalbus bus
    2. Take the bus from Port Authority Bus Terminal to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Myrtle Beach Bus Stationbus bus
    24h 15m
    $187–458

Buffalo to Myrtle Beach by bus

Calendar4Weekly Buses
Duration23h 15mAverage Duration
Ticket$176Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Myrtle Beach.ExpandLaunch map view
  • Distance: 654.5 mi
  • Duration: 5h 22m

What companies run services between Buffalo, NY, USA and Myrtle Beach, SC, USA?

Southwest Airlines, American Airlines, and Delta fly from Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR) every 3 hours. Alternatively, you can take a bus from Buffalo to Myrtle Beach Bus Station via Newark Penn Station and Fayetteville Bus Station in around 23h 15m.

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Want to know more about travelling around United States

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