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How to get fromBuffalo to Myrtle Beachby plane, bus (Greyhound), train, bus, car, or bus (Flixbus, Greyhound)

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There are 6 ways to get from Buffalo to Myrtle Beach by plane, bus (Greyhound), train, bus, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR)plane plane BUF - MYR
    5h 6m
    $87–422

  2. Bus

    1. Take the bus from Buffalo, NY to Robert K Pfaff Transit Center - Akronbus bus
    2. Take the bus from Robert K Pfaff Transit Center - Akron to Charleston, WVbus bus
    3. Take the bus from Charleston, WV to Charlotte Bus Stationbus bus
    4. Take the bus from Charlotte Bus Station to Camdenbus bus
    5. Take the bus from Camden to Myrtle Beach Bus Stationbus bus
    22h 35m
    $105–257

  3. Train, bus

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Fayetteville Amtrak Stationtrain train
    3. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    29h 54m
    $313–698

  4. Drive  760.8 mi

    1. Drive from Buffalo to Myrtle Beachcar car 760.8 mi
    15h 35m
    $139–201

  5. Bus to Rochester, fly

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Myrtle Beach (MYR)plane plane ROC - MYR
    4h 52m
    $229–757

  6. Bus via Washington

    1. Take the bus from Buffalo to Ithacabus bus
    2. Take the bus from Ithaca to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Fayetteville Bus Stationbus bus
    4. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    31h 55m
    $193–341

Buffalo to Myrtle Beach by bus

Calendar7Weekly Buses
Duration22h 35mAverage Duration
Ticket$105Cheapest Price
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Questions & Answers

Map of how to get from Buffalo to Myrtle Beach.ExpandLaunch map view
  • Distance: 652.7 mi
  • Duration: 5h 6m

What companies run services between Buffalo, NY, USA and Myrtle Beach, SC, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR) every 3 hours. Alternatively, you can take a bus from Buffalo, NY to Myrtle Beach Bus Station via Robert K Pfaff Transit Center - Akron, Charleston, WV, Charlotte Bus Station, and Camden in around 22h 35m.

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