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How to get fromBuffalo to Myrtle Beachby plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Flixbus, Greyhound)

Find Transport to Myrtle Beach

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There are 6 ways to get from Buffalo to Myrtle Beach by plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Buffalo Niagara International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR)plane plane BUF - MYR
    5h 7m
    $78–386

  2. Bus via Youngstown

    1. Take the bus from Buffalo, NY to Youngstown, OHbus bus
    2. Take the bus from Youngstown Bus Stop to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Raleigh Bus Stationbus bus
    4. Take the bus from Raleigh Bus Station to Myrtle Beach Bus Stationbus bus
    22h 25m
    $127–254

  3. Train, bus

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Fayetteville Amtrak Stationtrain train
    3. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    24h 9m
    $262–616

  4. Drive  760.8 mi

    1. Drive from Buffalo to Myrtle Beachcar car 760.8 mi
    15h 35m
    $139–201

  5. Bus to Rochester, fly

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Myrtle Beach (MYR)plane plane ROC - MYR
    4h 52m
    $130–605

  6. Bus

    1. Take the bus from Buffalo to Ithacabus bus
    2. Take the bus from Ithaca to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Fayetteville Bus Stationbus bus
    4. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    26h 10m
    $168–271

Buffalo to Myrtle Beach by bus

Calendar7Weekly Buses
Duration22h 25mAverage Duration
Ticket$127Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Myrtle Beach.ExpandLaunch map view
  • Distance: 654.5 mi
  • Duration: 5h 7m

What companies run services between Buffalo, NY, USA and Myrtle Beach, SC, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Myrtle Beach (MYR) hourly. Alternatively, you can take a bus from Buffalo, NY to Myrtle Beach Bus Station via Youngstown, OH, Youngstown Bus Stop, Washington Union Station, and Raleigh Bus Station in around 22h 25m.

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