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How to get fromBuffalo to Mysticby plane, train, train (Amtrak), bus, or car

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There are 10 ways to get from Buffalo to Mystic by plane, train, train (Amtrak), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Boston Logan Airport, train

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    2. Take the train from Boston to Mystic Stationtrain train
    5h 55m
    $121–481

  2. Drive  441.7 mi

    cheapest
    1. Drive from Buffalo to Mysticcar car 441.7 mi
    8h 7m
    $81–117

  3. Train (Amtrak)

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Mystic Stationtrain train Northeast Regional
    12h
    $311–490

  4. Bus, train via New York

    1. Take the bus from Buffalo to New York Midtownbus bus FlixBus 2686 / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Mystic Stationtrain train Northeast Regional
    12h 8m
    $137–219

  5. Fly Buffalo Niagara International Airport to Laguardia Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Laguardia Airport (LGA)plane plane BUF - LGA
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Mystic Stationtrain train
    7h 23m
    $145–608

  6. Fly Buffalo Niagara International Airport to John F. Kennedy International Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to John F. Kennedy International Airport (JFK)plane plane BUF - JFK
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Mystic Stationtrain train
    7h 20m
    $126–411

  7. Fly Buffalo Niagara International Airport to Newark Liberty International Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Newark Liberty International Airport (EWR)plane plane BUF - EWR
    2. Take the train from Newark Liberty International Airport to Mystic Stationtrain train
    7h 49m
    $122–412

  8. Bus to Rochester, fly to Boston Logan Airport, train

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane plane ROC - BOS
    3. Take the train from Boston to Mystic Stationtrain train
    7h 3m
    $164–622

  9. Fly Buffalo Niagara International Airport to Philadelphia International Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Philadelphia International Airport (PHL)plane plane BUF - PHL
    2. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Mystic Stationtrain train
    9h 1m
    $154–1,136

  10. Bus, train

    1. Take the bus from Buffalo to Springfield Union Stationbus bus
    2. Take the bus from Springfield to Hartfordbus bus
    3. Take the bus from Asylum St @ Bushnell Park to Old Saybrook RR Stnbus bus 921
    4. Take the train from Old Saybrook Amtrak Station to Mystic Stationtrain train
    13h 16m
    $90–135

Buffalo to Mystic by train (Amtrak)

Calendar21Weekly Trains
Duration12hAverage Duration
Ticket$311Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Mystic.ExpandLaunch map view
  • Distance: 511.8 mi
  • Duration: 5h 55m

What companies run services between Buffalo, NY, USA and Mystic, CT, USA?

You can take a train from Buffalo to Mystic Station via Ny Moynihan Train Hall At Penn Station in around 12h.

Airlines
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Bus operators

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