Rome2Rio

How to get fromBuffalo to North Carolinaby plane, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)

Find Transport to North Carolina

See all options

There are 8 ways to get from Buffalo to North Carolina by plane, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Charlotte Douglas International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Charlotte Douglas International Airport (CLT)plane plane BUF - CLT
    4h 8m
    $100–605

  2. Bus via Charleston

    cheapest
    1. Take the bus from Buffalo, NY to Robert K Pfaff Transit Center - Akronbus bus
    2. Take the bus from Robert K Pfaff Transit Center - Akron to Charleston, WVbus bus
    3. Take the bus from Charleston, WV to Charlotte Bus Stationbus bus
    15h 40m
    $83–196

  3. Train (Amtrak)

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Charlotte Amtrak Stationtrain train Crescent / ...
    22h 11m
    $266–659

  4. Drive  654.5 mi

    1. Drive from Buffalo to Charlottecar car 654.5 mi
    11h 11m
    $120–173

  5. Fly Buffalo Niagara International Airport to Raleigh-Durham International Airport

    1. Fly from Buffalo Niagara International Airport (BUF) to Raleigh-Durham International Airport (RDU)plane plane BUF - RDU
    4h 40m
    $125–415

  6. Bus to Rochester, fly to Charlotte Douglas International Airport

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Charlotte Douglas International Airport (CLT)plane plane ROC - CLT
    5h 21m
    $162–845

  7. Bus to Rochester, fly to Raleigh-Durham International Airport

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Raleigh-Durham International Airport (RDU)plane plane ROC - RDU
    5h 49m
    $142–695

  8. Bus

    1. Take the bus from Buffalo to Columbusbus bus FlixBus 2526
    2. Take the bus from Columbus to Charlottebus bus Bsb 32
    19h 2m
    $97–178

Buffalo to North Carolina by bus

Calendar7Weekly Buses
Duration15h 40mAverage Duration
Ticket$83Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Buffalo to North Carolina.ExpandLaunch map view
  • Distance: 565.8 mi
  • Duration: 4h 8m

What companies run services between Buffalo, NY, USA and North Carolina, USA?

American Airlines, Southwest Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Charlotte Douglas International Airport (CLT) every 3 hours. Alternatively, you can take a bus from Buffalo, NY to Charlotte Bus Station via Robert K Pfaff Transit Center - Akron and Charleston, WV in around 15h 40m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There