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How to get fromBuffalo to North Carolinaby plane, bus (Greyhound), train (Amtrak), car, or bus

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There are 8 ways to get from Buffalo to North Carolina by plane, bus (Greyhound), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Charlotte Douglas International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Charlotte Douglas International Airport (CLT)plane plane BUF - CLT
    3h 51m
    $135–781

  2. Bus via Charleston

    cheapest
    1. Take the bus from Buffalo, NY to Robert K Pfaff Transit Center - Akronbus bus
    2. Take the bus from Robert K Pfaff Transit Center - Akron to Charleston, WVbus bus
    3. Take the bus from Charleston, WV to Charlotte Bus Stationbus bus
    15h 40m
    $83–206

  3. Train (Amtrak)

    1. Take the train from Buffalo to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Charlotte Amtrak Stationtrain train Crescent / ...
    22h 11m
    $336–689

  4. Drive 654.5 mi

    1. Drive from Buffalo to Charlottecar car 654.5 mi
    11h 11m
    $120–173

  5. Fly Buffalo Niagara International Airport to Raleigh-Durham International Airport

    1. Fly from Buffalo Niagara International Airport (BUF) to Raleigh-Durham International Airport (RDU)plane plane BUF - RDU
    4h 21m
    $125–481

  6. Bus to Rochester, fly to Charlotte Douglas International Airport

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Charlotte Douglas International Airport (CLT)plane plane ROC - CLT
    5h 7m
    $163–798

  7. Bus to Rochester, fly to Raleigh-Durham International Airport

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Raleigh-Durham International Airport (RDU)plane plane ROC - RDU
    5h 37m
    $153–948

  8. Bus

    1. Take the bus from Buffalo to Akronbus bus
    2. Take the bus from Akron to Columbusbus bus
    3. Take the bus from Columbus to Charlottebus bus
    19h 10m

Buffalo to North Carolina by bus

Calendar7Weekly Buses
Duration15h 40mAverage Duration
Ticket$83Cheapest Price
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Questions & Answers

Map of how to get from Buffalo to North Carolina.ExpandLaunch map view
  • Distance: 564 mi
  • Duration: 3h 51m

What companies run services between Buffalo, NY, USA and North Carolina, USA?

American Airlines, United Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Charlotte Douglas International Airport (CLT) every 3 hours. Alternatively, you can take a bus from Buffalo, NY to Charlotte Bus Station via Robert K Pfaff Transit Center - Akron and Charleston, WV in around 15h 40m.

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