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How to get fromBuffalo to Northboroughby bus (Greyhound), train (Amtrak), car, plane, bus (Flixbus), train, or bus

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There are 7 ways to get from Buffalo to Northborough by bus (Greyhound), train (Amtrak), car, plane, bus (Flixbus), train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Buffalo to Springfield Union Stationbus bus Greyhound US0171
    2. Take the bus from Springfield to Worcesterbus bus Ppb 6726 / ...
    10h 20m
    $98–152

  2. Drive  425.3 mi

    cheapest
    1. Drive from Buffalo to Northboroughcar car 425.3 mi
    7h 27m
    $78–113

  3. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Worcester Union Stationtrain train Lake Shore Limited
    11h 57m
    $142–433

  4. Fly Buffalo Niagara International Airport to Worcester Regional Airport

    1. Fly from Buffalo Niagara International Airport (BUF) to Worcester Regional Airport (ORH)plane plane BUF - ORH
    6h 26m
    $102–427

  5. Bus via Ithaca

    1. Take the bus from Buffalo to Ithacabus bus
    2. Take the bus from Ithaca to Albany Bus Terminal, NYbus bus
    3. Take the bus from Albany Bus Terminal, NY to Worcester Union Stationbus bus
    14h 40m
    $91–164

  6. Fly Buffalo Niagara International Airport to Boston Logan Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    2. Take the train from Back Bay to Westboroughtrain train
    5h 30m
    $92–412

  7. Bus to Rochester, fly to Boston Logan Airport, train

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane plane ROC - BOS
    3. Take the train from Back Bay to Westboroughtrain train
    6h 35m
    $129–532

Buffalo Niagara International Airport (BUF) to Worcester Regional Airport (ORH) flights

Calendar24Weekly Planes
Duration5h 46mAverage Duration
Ticket$62Cheapest Price
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Questions & Answers

Map of how to get from Buffalo to Northborough.ExpandLaunch map view
  • Distance: 441.7 mi
  • Duration: 10h 20m

What companies run services between Buffalo, NY, USA and Northborough, MA, USA?

You can take a bus from Buffalo to Northborough via Springfield Union Station, Springfield, and Worcester in around 10h 20m. Alternatively, Amtrak operates a train from Buffalo Depew Station to Worcester Union Station once daily. Tickets cost $110–260 and the journey takes 10h 25m.

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