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How to get fromBuffalo to Portlandby plane, bus (Greyhound, Amtrak), train, bus, car, or bus (Flixbus, Amtrak)

Find Transport to Portland

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There are 6 ways to get from Buffalo to Portland by plane, bus (Greyhound, Amtrak), train, bus, car, or bus (Flixbus, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Portland

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Portland (PWM)plane plane BUF - PWM
    5h 21m
    $77–442

  2. Bus

    1. Take the bus from Buffalo to Bostonbus bus Greyhound US0171
    2. Take the bus from Boston, MA - South Station to Portland, MEbus bus Logan Airport / ...
    12h 18m
    $104–167

  3. Train, bus

    1. Take the train from Buffalo Depew Station to Bostontrain train Lake Shore Limited
    2. Take the bus from Boston, MA - South Station to Portland, MEbus bus Logan Airport / ...
    14h 57m
    $293–599

  4. Drive  509.3 mi

    1. Drive from Buffalo to Portlandcar car 509.3 mi
    10h 22m
    $93–135

  5. Fly to Boston Logan Airport, bus

    1. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    2. Take the bus from Logan International Airport to Portland, MEbus bus
    5h 44m
    $85–427

  6. Bus via Ithaca

    1. Take the bus from Buffalo to Ithacabus bus
    2. Take the bus from Ithaca to Bostonbus bus
    3. Take the bus from Boston, MA - South Station to Portland, MEbus bus
    14h 53m
    $101–173

Buffalo to Portland by bus

Calendar7Weekly Buses
Duration12h 18mAverage Duration
Ticket$104Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to Portland.ExpandLaunch map view
  • Distance: 438.6 mi
  • Duration: 5h 21m

What companies run services between Buffalo, NY, USA and Portland, ME, USA?

Southwest Airlines, United Airlines, and three other airlines fly from Buffalo Niagara International Airport (BUF) to Portland (PWM) hourly. Alternatively, you can take a bus from Buffalo to Portland, ME via Boston and Boston, MA - South Station in around 12h 18m.

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Need to know: Greyhound

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