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How to get fromBuffalo to Salemby plane, bus, train (Amtrak), bus (Greyhound), car, train, shuttle, or taxi

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There are 10 ways to get from Buffalo to Salem by plane, bus, train (Amtrak), bus (Greyhound), car, train, shuttle, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Lambert–St. Louis International Airport, bus

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Lambert–St. Louis International Airport (STL)plane plane BUF - STL
    2. Take the bus from St Louis Bus Station to Mount Vernonbus bus
    8h 18m
    $215–873

  2. Drive 682.8 mi

    cheapest
    1. Drive from Buffalo to Salemcar car 682.8 mi
    11h 39m
    $125–180

  3. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to Centralia Amtraktrain train Saluki / ...
    17h 42m
    $277–702

  4. Bus

    1. Take the bus from Buffalo, NY to Cincinnati, OHbus bus
    2. Take the bus from Greyhound Station Cincinnati to Louisville, KY Bus Stationbus bus
    3. Take the bus from Louisville, KY to Evansville, INbus bus
    4. Take the bus from Evansville Bus Station to Mount Vernonbus bus
    19h 10m
    $158–291

  5. Fly Buffalo Niagara International Airport to Williamson County Regional Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Williamson County Regional Airport (MWA)plane plane BUF - MWA
    2. Take the train from Carbondale to Centralia Amtraktrain train
    9h 39m
    $188–703

  6. Fly Buffalo Niagara International Airport to Chicago Midway International Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane plane BUF - MDW
    2. Take the train from Chicago Union Station to Centralia Amtraktrain train
    9h 34m
    $286–621

  7. Shuttle to Toronto Pearson International Airport, fly to Lambert–St. Louis International Airport, bus

    1. Take a shuttle bus from Buffalo Airport to Pearson International Airport Terminal 1shuttle bus
    2. Fly from Toronto Pearson International Airport (YYZ) to Lambert–St. Louis International Airport (STL)plane plane YYZ - STL
    3. Take the bus from St Louis Bus Station to Mount Vernonbus bus
    10h 15m
    $255–723

  8. Fly Buffalo Niagara International Airport to Chicago O'Hare International Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)plane plane BUF - ORD
    2. Take the train from Chicago Union Station to Centralia Amtraktrain train
    9h 55m
    $293–548

  9. Fly Buffalo Niagara International Airport to Decatur Airport, bus, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Decatur Airport (DEC)plane plane BUF - DEC
    2. Take the bus from Decatur Downtown Transportation Center to Champaign Intermodal Trans Ctrbus bus
    3. Take the train from Champaign-Urbana to Centralia Amtraktrain train
    11h 7m
    $192–688

  10. Bus, taxi

    1. Take the bus from Buffalo, Ny to Pittsburgh, Pabus bus 530
    2. Take the bus from Pittsburgh Intermodal Station to Effinghambus bus
    3. Take the taxi from Effingham to Salemtaxi taxi
    20h 56m
    $226–493

Buffalo Niagara International Airport (BUF) to Lambert–St. Louis International Airport (STL) flights

Calendar118Weekly Planes
Duration5h 16mAverage Duration
Ticket$142Cheapest Price
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Questions & Answers

Map of how to get from Buffalo to Salem.ExpandLaunch map view
  • Distance: 797.8 mi
  • Duration: 8h 18m

What companies run services between Buffalo, NY, USA and Salem, Marion County, IL, USA?

You can take a train from Buffalo to Salem via Buffalo Depew Station, Chicago Union Station, and Centralia Amtrak in around 17h 42m. Alternatively, you can take a bus from Buffalo, NY to Salem via Cincinnati, OH, Greyhound Station Cincinnati, Louisville, KY, Evansville Bus Station, and Mount Vernon in around 19h 10m.

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