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How to get fromBuffalo to San Antonioby plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or train

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There are 8 ways to get from Buffalo to San Antonio by plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to San Antonio International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to San Antonio International Airport (SAT)plane plane BUF - SAT
    7h 42m
    $164–804

  2. Fly Buffalo Niagara International Airport to Austin-Bergstrom International Airport, bus

    cheapest
    1. Fly from Buffalo Niagara International Airport (BUF) to Austin-Bergstrom International Airport (AUS)plane plane BUF - AUS
    2. Take the bus from Austin, TX - UT Austin to San Antonio, TX - E Commerce Stbus bus
    10h 18m
    $162–732

  3. Bus

    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Dallas Bus Stationbus bus
    4. Take the bus from Dallas Bus Station to San Antonio Bus Stationbus bus
    38h
    $276–468

  4. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to San Antonio Stationtrain train Texas Eagle
    45h 26m
    $992–1,684

  5. Drive  1,624.9 mi

    1. Drive from Buffalo to San Antoniocar car 1,624.9 mi
    26h 47m
    $297–429

  6. Bus to Rochester, fly to San Antonio International Airport

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to San Antonio International Airport (SAT)plane plane ROC - SAT
    9h 18m
    $252–1,045

  7. Bus to Toronto Pearson International Airport, fly to San Antonio International Airport

    1. Take the bus from Buffalo to Mississaugabus bus
    2. Fly from Toronto Pearson International Airport (YYZ) to San Antonio International Airport (SAT)plane plane YYZ - SAT
    9h 34m
    $168–711

  8. Train, bus

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the bus from Chicago to Tornado Bus Co - San Antoniobus bus Chicago
    39h 10m
    $518–741

Buffalo to San Antonio by bus

Calendar7Weekly Buses
Duration38hAverage Duration
Ticket$276Cheapest Price
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Comparing Your Travel Options

Map of how to get from Buffalo to San Antonio.ExpandLaunch map view
  • Distance: 1,452.9 mi
  • Duration: 7h 42m

What companies run services between Buffalo, NY, USA and San Antonio, TX, USA?

Southwest Airlines, Delta, and American Airlines fly from Buffalo Niagara International Airport (BUF) to San Antonio International Airport (SAT) every 3 hours. Alternatively, you can take a bus from Buffalo to San Antonio Bus Station via Cleveland Bus Station, Nashville Bus Station, and Dallas Bus Station in around 38h.

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