There are 8 ways to get from Buffalo to San Francisco by plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Buffalo Niagara International Airport to San Francisco International Airport
best- Fly from Buffalo Niagara International Airport (BUF) to San Francisco International Airport (SFO)plane BUF - SFO
9h 11m$135–590Train (Amtrak)
- Take the train from Buffalo Depew Station to Chicago Union Stationtrain Lake Shore Limited
- Take the train from Chicago Union Station to Richmondtrain California Zephyr
2d 18h$1,586–2,690Bus
- Take the bus from Buffalo to Columbusbus
- Take the bus from Columbus to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Los Angeles Union Stationbus
- Take the bus from Los Angeles Union Station to San Franciscobus
2d 19h$510–845Drive 2,641.9 mi
- Drive from Buffalo to San Franciscocar 2,641.9 mi
41h 38m$452–653Fly Buffalo Niagara International Airport to Oakland International Airport
- Fly from Buffalo Niagara International Airport (BUF) to Oakland International Airport (OAK)plane BUF - OAK
9h 23m$181–736Fly Buffalo Niagara International Airport to Norman Y. Mineta San José International Airport, Caltrain
- Fly from Buffalo Niagara International Airport (BUF) to Norman Y. Mineta San José International Airport (SJC)plane BUF - SJC
- Take the train from Santa Clara Caltrain Northbound to San Francisco Caltrain Northboundtrain
10h 38m$198–793Bus to Toronto Pearson International Airport, fly to San Francisco International Airport
- Take the bus from Buffalo to Torontobus
- Fly from Toronto Pearson International Airport (YYZ) to San Francisco International Airport (SFO)plane YYZ - SFO
11h 41m$225–739Bus to Toronto Pearson International Airport, fly to Oakland International Airport
- Take the bus from Buffalo to Torontobus
- Fly from Toronto Pearson International Airport (YYZ) to Oakland International Airport (OAK)plane YYZ - OAK
13h 18m$161–635
Buffalo to San Francisco by train and subway (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Buffalo to San Francisco is to fly which costs $130 - $600 and takes 9h 11m.
The fastest way to get from Buffalo to San Francisco is to fly which takes 9h 11m and costs $130 - $600.
No, there is no direct bus from Buffalo to San Francisco. However, there are services departing from Buffalo and arriving at San Francisco via Columbus, St Louis Bus Station and Los Angeles Union Station. The journey, including transfers, takes approximately 2 days 19h.
No, there is no direct train from Buffalo to San Francisco. However, there are services departing from Buffalo and arriving at Civic Center / UN Plaza via Buffalo Depew Station, Chicago Union Station and Richmond. The journey, including transfers, takes approximately 2 days 18h.
The distance between Buffalo and San Francisco is 2342 miles. The road distance is 2657.3 miles.
The best way to get from Buffalo to San Francisco without a car is to train which takes 2 days 18h and costs $1,500 - $2,700.
It takes approximately 9h 11m to get from Buffalo to San Francisco, including transfers.
Buffalo to San Francisco bus services, operated by Barons Bus, depart from Buffalo station.
Buffalo to San Francisco train services, operated by Amtrak, depart from Buffalo Depew Station.
The best way to get from Buffalo to San Francisco is to fly which takes 9h 11m and costs $130 - $600. Alternatively, you can train, which costs $1,500 - $2,700 and takes 2 days 18h, you could also bus, which costs $500 - $850 and takes 2 days 19h.
What companies run services between Buffalo, NY, USA and San Francisco, CA, USA?
Delta, Southwest Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to San Francisco International Airport (SFO) hourly. Alternatively, you can take a train from Buffalo to Civic Center / UN Plaza via Buffalo Depew Station, Chicago Union Station, Richmond, and Richmond in around 2d 18h.
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to San Francisco International Airport via Denver
- Ave. Duration
- 7h 50m
- When
- Every day
- Estimated price
- $120–550
Flights from Buffalo Niagara International Airport to San Francisco International Airport via Chicago Midway
- Ave. Duration
- 8h 36m
- When
- Every day
- Estimated price
- $120–550
Flights from Buffalo Niagara International Airport to San Francisco International Airport via Las Vegas
- Ave. Duration
- 11h 15m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $130–550
Flights from Buffalo Niagara International Airport to Oakland International Airport via Denver
- Ave. Duration
- 7h 25m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $170–700
Flights from Buffalo Niagara International Airport to Oakland International Airport via Chicago Midway
- Ave. Duration
- 8h 11m
- When
- Every day
- Estimated price
- $170–700
Flights from Buffalo Niagara International Airport to Oakland International Airport via Las Vegas
- Ave. Duration
- 8h 10m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $170–700
Flights from Buffalo Niagara International Airport to Oakland International Airport via Phoenix
- Ave. Duration
- 10h 15m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $180–750
Flights from Buffalo Niagara International Airport to Norman Y. Mineta San José International Airport via Chicago Midway
- Ave. Duration
- 8h 1m
- When
- Every day
- Estimated price
- $180–750
Flights from Buffalo Niagara International Airport to Norman Y. Mineta San José International Airport via Phoenix
- Ave. Duration
- 8h
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $200–800
Flights from Buffalo Niagara International Airport to Norman Y. Mineta San José International Airport via Denver
- Ave. Duration
- 8h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $180–750
Flights from Buffalo Niagara International Airport to Norman Y. Mineta San José International Airport via Las Vegas
- Ave. Duration
- 8h 15m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $180–800
Flights from Toronto Pearson International Airport to Oakland International Airport via Denver
- Ave. Duration
- 7h 52m
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $140–600
Flights from Toronto Pearson International Airport to Oakland International Airport via Los Angeles
- Ave. Duration
- 8h 15m
- When
- Saturday
- Estimated price
- $150–650
Flights from Toronto Pearson International Airport to Oakland International Airport via Las Vegas
- Ave. Duration
- 8h 25m
- When
- Tuesday and Wednesday
- Estimated price
- $140–600
Flights from Toronto Pearson International Airport to Oakland International Airport via San Diego
- Ave. Duration
- 8h 30m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $160–650
- Website
- united.com
Flights from Buffalo Niagara International Airport to San Francisco International Airport via Chicago O'Hare
- Ave. Duration
- 8h 22m
- When
- Every day
- Estimated price
- $120–550
Flights from Buffalo Niagara International Airport to San Francisco International Airport via Denver
- Ave. Duration
- 9h 21m
- When
- Every day
- Estimated price
- $120–550
Flights from Buffalo Niagara International Airport to Norman Y. Mineta San José International Airport via Denver
- Ave. Duration
- 7h 28m
- When
- Every day
- Estimated price
- $180–750
Flights from Buffalo Niagara International Airport to Norman Y. Mineta San José International Airport via Chicago O'Hare
- Ave. Duration
- 8h 31m
- When
- Every day
- Estimated price
- $180–750
Flights from Toronto Pearson International Airport to San Francisco International Airport
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $100–430
Flights from Toronto Pearson International Airport to San Francisco International Airport via Denver
- Ave. Duration
- 8h
- When
- Every day
- Estimated price
- $100–430
- Website
- aircanada.com
Flights from Buffalo Niagara International Airport to San Francisco International Airport via Chicago O'Hare
- Ave. Duration
- 8h 22m
- When
- Every day
- Estimated price
- $120–550
Flights from Toronto Pearson International Airport to San Francisco International Airport
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $100–430
Flights from Toronto Pearson International Airport to San Francisco International Airport via Denver
- Ave. Duration
- 8h
- When
- Every day
- Estimated price
- $100–430
- Website
- delta.com
Flights from Buffalo Niagara International Airport to San Francisco International Airport via Minneapolis
- Ave. Duration
- 7h 27m
- When
- Tuesday
- Estimated price
- $120–550
Flights from Buffalo Niagara International Airport to San Francisco International Airport via Detroit
- Ave. Duration
- 8h 39m
- When
- Every day
- Estimated price
- $120–550
Flights from Toronto Pearson International Airport to San Francisco International Airport via Salt Lake City
- Ave. Duration
- 7h 26m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $100–430
Flights from Toronto Pearson International Airport to San Francisco International Airport via Minneapolis
- Ave. Duration
- 8h 41m
- When
- Every day
- Estimated price
- $100–430
Flights from Toronto Pearson International Airport to Oakland International Airport via Salt Lake City
- Ave. Duration
- 7h 13m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $140–600
- Website
- aa.com
Flights from Buffalo Niagara International Airport to San Francisco International Airport via Chicago O'Hare
- Ave. Duration
- 9h 46m
- When
- Every day
- Estimated price
- $120–550
Flights from Toronto Pearson International Airport to San Francisco International Airport
- Ave. Duration
- 5h 54m
- When
- Every day
- Estimated price
- $280–700
- Website
- flyporter.com
Flights from Toronto Pearson International Airport to San Francisco International Airport
- Ave. Duration
- 5h 54m
- When
- Every day
- Estimated price
- $280–700
- Website
- jsx.com
Flights from Toronto Pearson International Airport to Oakland International Airport via Las Vegas
- Ave. Duration
- 7h 35m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $270–950
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Buffalo Depew Station to Chicago Union Station
- Ave. Duration
- 10h 33m
- Frequency
- Twice daily
- Estimated price
- $280–450
- Website
- Amtrak
Train from Chicago Union Station to Richmond
- Ave. Duration
- 2d 4h
- Frequency
- Once daily
- Estimated price
- $1,300–2,100
- Website
- Amtrak
- Phone
- +1 800-660-4287
- Website
- Cal Train
Train from Santa Clara Caltrain Northbound to San Francisco Caltrain Northbound
- Ave. Duration
- 1h 12m
- Frequency
- Every 30 minutes
- Estimated price
- $9–12
- Website
- Cal Train
- Schedules at
- Cal Train
- One-way Adult
- $9–12
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Buffalo to Columbus
- Ave. Duration
- 7h
- Frequency
- Once daily
- Estimated price
- $35–80
- Website
- Barons Bus
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Columbus to St Louis Bus Station
- Ave. Duration
- 9h 25m
- Frequency
- Every 4 hours
- Estimated price
- $75–120
- Website
- Greyhound
Bus from St Louis Bus Station to Los Angeles Union Station
- Ave. Duration
- 40h 30m
- Frequency
- Twice daily
- Estimated price
- $340–550
- Website
- Greyhound
Bus from Buffalo to Toronto
- Ave. Duration
- 2h 45m
- Frequency
- Every 4 hours
- Estimated price
- $18–27
- Website
- Greyhound
Bus from Buffalo to Toronto
- Ave. Duration
- 2h 45m
- Frequency
- Every 4 hours
- Estimated price
- $18–27
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Los Angeles Union Station to San Francisco
- Ave. Duration
- 7h 35m
- Frequency
- 3 times a day
- Estimated price
- $60–95
- Schedules at
- Flixbus USA
Bus from Buffalo to Toronto
- Ave. Duration
- 3h 25m
- Frequency
- Every 4 hours
- Estimated price
- $15–24
- Schedules at
- Flixbus USA
Bus from Buffalo to Toronto
- Ave. Duration
- 3h 25m
- Frequency
- Every 4 hours
- Estimated price
- $15–24
- Schedules at
- Flixbus USA
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Booking & Getting There
Buffalo to San Francisco bus services, operated by Barons Bus, arrive at Columbus station.
San Francisco is 3h behind Buffalo. It is currently 3:35 AM in Buffalo and 12:35 AM in San Francisco.
Buffalo to San Francisco train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Buffalo to San Francisco is 2657 miles. It takes approximately 41h 38m to drive from Buffalo to San Francisco.
Book your Buffalo to San Francisco bus tickets online with Omio.
There are 808+ hotels available in San Francisco.
















